Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MALEEEEESQ NAPFCVLDGL FCEEESEFHE QVDLCDESVE KFPFLNLGLS DHDMLWDDDE

70 80 90 100 110 120
LSTLISKQEP CLYDEILDDE FLVLCREKAL DWIFKVKSHY GFNSLTALLA VNYFDRFITS

130 140 150 160 170 180
RKFQTDKPWM SQLTALACLS LAAKVEEIRV PFLLDFQVEE ARYVFEAKTI QRMELLVLST

190 200 210 220 230 240
LDWRMHPVTP ISFFDHIIRR YSFKSHHQLE FLSRCESLLL SIIPDSRFLS FSPSVLATAI

250 260 270 280 290 300
MVSVIRDLKM CDEAVYQSQL MTLLKVDSEK VNKCYELVLD HSPSKKRMMN WMQQPASPIG

310 320 330 340 350 360
VFDASFSSDS SNESWVVSAS ASVSSSPSSE PLLKRRRVQE QQMRLSSINR MFFDVLSSSP


R


References and documentation are available.

Number of amino acids: 361 Molecular weight: 41737.74 Theoretical pI: 4.84
Amino acid composition: 
Ala (A) 18 5.0% Arg (R) 19 5.3% Asn (N) 8 2.2% Asp (D) 25 6.9% Cys (C) 9 2.5% Gln (Q) 15 4.2% Glu (E) 31 8.6% Gly (G) 4 1.1% His (H) 8 2.2% Ile (I) 15 4.2% Leu (L) 45 12.5% Lys (K) 17 4.7% Met (M) 13 3.6% Phe (F) 24 6.6% Pro (P) 15 4.2% Ser (S) 47 13.0% Thr (T) 10 2.8% Trp (W) 6 1.7% Tyr (Y) 7 1.9% Val (V) 25 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 56 Total number of positively charged residues (Arg + Lys): 36 Atomic composition: Carbon C 1866 Hydrogen H 2898 Nitrogen N 480 Oxygen O 561 Sulfur S 22 Formula: C1866H2898N480O561S22 Total number of atoms: 5827 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 43930 Abs 0.1% (=1 g/l) 1.053, assuming all pairs of Cys residues form cystines Ext. coefficient 43430 Abs 0.1% (=1 g/l) 1.041, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 63.66 This classifies the protein as unstable. Aliphatic index: 89.89 Grand average of hydropathicity (GRAVY): -0.134