Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MALEPIDYTT HSREIDAEYL KIVRGSDPDT TWLIISPNAK KEYEPESTGS SFHDFLQLFD

70 80 90 100 110 120
ETKVQYGLAR VSPPGSDVEK IIIIGWCPDS APLKTRASFA ANFAAVANNL FKGYHVQVTA

130 140 150 160 170 180
RDEDDLDENE LLMKISNAAG ARYSIQTSSK QQGKASTPPV KKSFTPSKSP APVSKKEPVK

190 200 210 220 230 240
TPSPAPAAKI SSRVNDNNDD DDWNEPELKE RDFDQAPLKP NQSSYKPIGK IDLQKVIAEE

250 260 270 280 290 300
KAKEDPRLVQ KPTAAGSKID PSSDIANLKN ESKLKRDSEF NSFLGTTKPP SMTESSLKND

310 320 330 340 350 360
DDKVIKGFRN EKSPAQLWAE RKAKQNSGNA ETKAEAPKPE VPEDEPEGEP DVKDLKSKFE

370 380 390 400 410 420
GLAASEKEEE EMENKFAPPP KKSEPTIISP KPFSKPQEPV KAEEAEQPKT DYKKIGNPLP

430 440 450 460 470 480
GMHIEADNEE EPEENDDDWD DDEDEAAQPP LPSRNVASGA PVQKEEPEQE EIAPSLPSRN

490 500 510 520 530 540
SIPAPKQEEA PEQAPEEEIE EEAEEAAPQL PSRSSAAPPP PPRRATPEKK PKENPWATAE

550 560 570 580 590
YDYDAAEDNE LTFVENDKII NIEFVDDDWW LGELEKDGSK GLFPSNYVSL GN


References and documentation are available.

Number of amino acids: 592 Molecular weight: 65576.22 Theoretical pI: 4.59
Amino acid composition: 
Ala (A) 56 9.5% Arg (R) 17 2.9% Asn (N) 30 5.1% Asp (D) 47 7.9% Cys (C) 1 0.2% Gln (Q) 20 3.4% Glu (E) 75 12.7% Gly (G) 22 3.7% His (H) 4 0.7% Ile (I) 28 4.7% Leu (L) 31 5.2% Lys (K) 59 10.0% Met (M) 5 0.8% Phe (F) 17 2.9% Pro (P) 66 11.1% Ser (S) 51 8.6% Thr (T) 22 3.7% Trp (W) 8 1.4% Tyr (Y) 11 1.9% Val (V) 22 3.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 122 Total number of positively charged residues (Arg + Lys): 76 Atomic composition: Carbon C 2878 Hydrogen H 4488 Nitrogen N 768 Oxygen O 971 Sulfur S 6 Formula: C2878H4488N768O971S6 Total number of atoms: 9111 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 60390 Abs 0.1% (=1 g/l) 0.921, assuming all pairs of Cys residues form cystines Ext. coefficient 60390 Abs 0.1% (=1 g/l) 0.921, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 61.76 This classifies the protein as unstable. Aliphatic index: 59.10 Grand average of hydropathicity (GRAVY): -1.042