ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MALERELLVA TQAVRKASLL TKRIQSEVIS HKDSTTITKN DNSPVTTGDY AAQTIIINAI 

        70         80         90        100        110        120 
KSNFPDDKVV GEESSSGLSD AFVSGILNEI KANDEVYNKN YKKDDFLFTN DQFPLKSLED 

       130        140        150        160        170        180 
VRQIIDFGNY EGGRKGRFWC LDPIDGTKGF LRGEQFAVCL ALIVDGVVQL GCIGCPNLVL 

       190        200        210        220        230        240 
SSYGAQDLKG HESFGYIFRA VRGLGAFYSP SSDAESWTKI HVRHLKDTKD MITLEGVEKG 

       250        260        270        280        290        300 
HSSHDEQTAI KNKLNISKSL HLDSQAKYCL LALGLADVYL RLPIKLSYQE KIWDHAAGNV 

       310        320        330        340        350 
IVHEAGGIHT DAMEDVPLDF GNGRTLATKG VIASSGPREL HDLVVSTSCD VIQSRNA 

References and documentation are available.

Number of amino acids: 357

Molecular weight: 39149.28

Theoretical pI: 5.79

Amino acid composition: 
Ala (A)  26	  7.3%
Arg (R)  14	  3.9%
Asn (N)  16	  4.5%
Asp (D)  28	  7.8%
Cys (C)   6	  1.7%
Gln (Q)  12	  3.4%
Glu (E)  19	  5.3%
Gly (G)  29	  8.1%
His (H)  11	  3.1%
Ile (I)  25	  7.0%
Leu (L)  35	  9.8%
Lys (K)  25	  7.0%
Met (M)   3	  0.8%
Phe (F)  13	  3.6%
Pro (P)   9	  2.5%
Ser (S)  30	  8.4%
Thr (T)  18	  5.0%
Trp (W)   3	  0.8%
Tyr (Y)  10	  2.8%
Val (V)  25	  7.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 47
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      1732
Hydrogen    H	      2747
Nitrogen    N	       477
Oxygen      O	       538
Sulfur      S	         9

Formula: C1732H2747N477O538S9
Total number of atoms: 5503

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    31775
Abs 0.1% (=1 g/l)   0.812, assuming all pairs of Cys residues form cystines


Ext. coefficient    31400
Abs 0.1% (=1 g/l)   0.802, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.42
This classifies the protein as stable.



Aliphatic index: 93.14

Grand average of hydropathicity (GRAVY): -0.230