ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MALSSLLRSA ATSAAAPRVE LYPSSSYNHS QVTSSLGFSH SLTSSRFSGA AVSTGKYNAK 

        70         80         90        100        110        120 
RVQPIKATAT EAPPAVHRSR SSGKTKVGIN GFGRIGRLVL RIATFRDDIE VVAVNDPFID 

       130        140        150        160        170        180 
AKYMAYMFKY DSTHGNYKGT INVIDDSTLE INGKQVKVVS KRDPAEIPWA DLGAEYVVES 

       190        200        210        220        230        240 
SGVFTTVGQA SSHLKGGAKK VIISAPSADA PMFVVGVNEK TYLPNMDIVS NASCTTNCLA 

       250        260        270        280        290        300 
PLAKVVHEEF GILEGLMTTV HATTATQKTV DGPSMKDWRG GRGASQNIIP SSTGAAKAVG 

       310        320        330        340        350        360 
KVLPELNGKL TGMAFRVPTP NVSVVDLTCR LEKDASYEDV KAAIKFASEG PLRGILGYTE 

       370        380        390        400        410        420 
EDVVSNDFLG DSRSSIFDAN AGIGLSKSFM KLVSWYDNEW GYSNRVLDLI EHMALVAASR 

References and documentation are available.

Number of amino acids: 420

Molecular weight: 44845.89

Theoretical pI: 8.73

Amino acid composition: 
Ala (A)  44	 10.5%
Arg (R)  19	  4.5%
Asn (N)  18	  4.3%
Asp (D)  22	  5.2%
Cys (C)   3	  0.7%
Gln (Q)   6	  1.4%
Glu (E)  19	  4.5%
Gly (G)  34	  8.1%
His (H)   8	  1.9%
Ile (I)  21	  5.0%
Leu (L)  29	  6.9%
Lys (K)  26	  6.2%
Met (M)  10	  2.4%
Phe (F)  14	  3.3%
Pro (P)  18	  4.3%
Ser (S)  46	 11.0%
Thr (T)  27	  6.4%
Trp (W)   4	  1.0%
Tyr (Y)  13	  3.1%
Val (V)  39	  9.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      1980
Hydrogen    H	      3153
Nitrogen    N	       547
Oxygen      O	       613
Sulfur      S	        13

Formula: C1980H3153N547O613S13
Total number of atoms: 6306

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    41495
Abs 0.1% (=1 g/l)   0.925, assuming all pairs of Cys residues form cystines


Ext. coefficient    41370
Abs 0.1% (=1 g/l)   0.922, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 37.00
This classifies the protein as stable.



Aliphatic index: 83.83

Grand average of hydropathicity (GRAVY): -0.108