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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MANDGIQRND NRKGFKTVQF SAYSKEIDVI MKKISFLERN ITQQLDTLPH FPKTLPPNHK

70 80 90 100 110 120
DCVSRKHRAR RGWSSQLKNL LGIYSKEEIF TLDNLAATLH DQVLKLQATL FPNAILKQVH

130 140 150 160 170 180
LDNANIENKR ILKEITYKYL SNENCKEENK FGTFIVKRIF FGDLSLGVSV LINRIAFESA

190 200 210 220 230
TSSIMVVRSS FIESDFFYED YLIFDCRAKR RKKLKRKILF ISTTMNFNYQ TKV


References and documentation are available.

Number of amino acids: 233 Molecular weight: 27228.56 Theoretical pI: 9.76
Amino acid composition: 
Ala (A) 11 4.7% Arg (R) 15 6.4% Asn (N) 17 7.3% Asp (D) 12 5.2% Cys (C) 3 1.3% Gln (Q) 9 3.9% Glu (E) 12 5.2% Gly (G) 7 3.0% His (H) 5 2.1% Ile (I) 20 8.6% Leu (L) 23 9.9% Lys (K) 24 10.3% Met (M) 4 1.7% Phe (F) 17 7.3% Pro (P) 5 2.1% Ser (S) 17 7.3% Thr (T) 13 5.6% Trp (W) 1 0.4% Tyr (Y) 7 3.0% Val (V) 11 4.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 24 Total number of positively charged residues (Arg + Lys): 39 Atomic composition: Carbon C 1229 Hydrogen H 1959 Nitrogen N 339 Oxygen O 345 Sulfur S 7 Formula: C1229H1959N339O345S7 Total number of atoms: 3879 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 16055 Abs 0.1% (=1 g/l) 0.590, assuming all pairs of Cys residues form cystines Ext. coefficient 15930 Abs 0.1% (=1 g/l) 0.585, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.55 This classifies the protein as unstable. Aliphatic index: 90.39 Grand average of hydropathicity (GRAVY): -0.384