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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MANDGNGDNN DDPLRQYLMN PRINPPPPSL LTLPENNDVT IPMPITPLEL KNRLIFGSFV

70 80 90 100 110 120
RSRKESSLPI DALSQNPSTS SSATTSFSDS TDLLLPLTEP NKPVRKSKPT INFHRSKTAP

130 140 150 160 170 180
AMAAINNISH PNDPKTDQQS DSKTIVNQAV ALLVVYLSLG VLIYWLNRDS YNVKQTHPVV

190 200 210 220 230 240
DALYFCIVTM CTIGYGDITP DSVVTKLFSI FFVLVGFGFM DILLSGMVTY VLDLQENYML

250 260 270 280 290 300
ETARNESLNL NDRDKVRSYI IDVKKGRMRI RLKVGLALGV VVLCLGFGVL IMHFVEKIGW

310 320 330 340 350 360
LDSFYFSVMS VTTVGYGDRA FNTLAGRLLA AMWLLVSTLA VARAILFLAE SRVDKRNRER

370 380 390 400 410 420
AKKVLGESMS ISQFLDADID CNGCVSKAEF VIYKLKKMDK ITEKDINPIG FQFDKLDRTN

430 440
SGRITLLDLL ESSTKDLPTA TSI


References and documentation are available.

Number of amino acids: 443 Molecular weight: 49326.13 Theoretical pI: 8.43
Amino acid composition: 
Ala (A) 24 5.4% Arg (R) 23 5.2% Asn (N) 27 6.1% Asp (D) 32 7.2% Cys (C) 5 1.1% Gln (Q) 9 2.0% Glu (E) 14 3.2% Gly (G) 22 5.0% His (H) 4 0.9% Ile (I) 29 6.5% Leu (L) 54 12.2% Lys (K) 26 5.9% Met (M) 14 3.2% Phe (F) 20 4.5% Pro (P) 23 5.2% Ser (S) 38 8.6% Thr (T) 29 6.5% Trp (W) 3 0.7% Tyr (Y) 12 2.7% Val (V) 35 7.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 46 Total number of positively charged residues (Arg + Lys): 49 Atomic composition: Carbon C 2209 Hydrogen H 3547 Nitrogen N 585 Oxygen O 651 Sulfur S 19 Formula: C2209H3547N585O651S19 Total number of atoms: 7011 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 34630 Abs 0.1% (=1 g/l) 0.702, assuming all pairs of Cys residues form cystines Ext. coefficient 34380 Abs 0.1% (=1 g/l) 0.697, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.53 This classifies the protein as stable. Aliphatic index: 101.40 Grand average of hydropathicity (GRAVY): 0.004