Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MANEGSDPLL QYMISPRLKK PPQLLFPLPE DNEVAIPMPM TPSEFKERLI FGPFSCSPRD

70 80 90 100 110 120
SSHFIDSMKQ PSPSSSSTAV NNPFSDSSTL DPLLPPPPPQ PEPWLSDQTS SHCQGHALHR

130 140 150 160 170 180
SKTAPAMAVI NDLHHPIRQK DPTETSRSVV RQAFALLVVY LSLGVLIYWL NRDHYVVNQT

190 200 210 220 230 240
HPVVDGLYFC IVTMCTIGYG DITPNSVVTK LFSIMFVLVG FGFIDILLSG MVSYVLDLQE

250 260 270 280 290 300
SYMLDSAKRR DEPEKRRSYI IDVKKGRMRI RLKVALALGV VVLCIAVGVG IMHFIEEIGW

310 320 330 340 350 360
LDSFYLSVMS VTTVGYGDRA FKTLPGRLFA AIWLLVSTLA VARAFLYLAE ARVDKRNRER

370 380 390 400 410 420
AKKVLCETMS VSQFFAADID NNGCVSKAEY VIYKLKEMEK ITDKDILPIS KQFDKLDRCS

430
NGKITLLDLL EGGSGD


References and documentation are available.

Number of amino acids: 436 Molecular weight: 48731.63 Theoretical pI: 7.10
Amino acid composition: 
Ala (A) 25 5.7% Arg (R) 23 5.3% Asn (N) 12 2.8% Asp (D) 28 6.4% Cys (C) 8 1.8% Gln (Q) 12 2.8% Glu (E) 19 4.4% Gly (G) 23 5.3% His (H) 9 2.1% Ile (I) 27 6.2% Leu (L) 48 11.0% Lys (K) 24 5.5% Met (M) 15 3.4% Phe (F) 20 4.6% Pro (P) 30 6.9% Ser (S) 40 9.2% Thr (T) 19 4.4% Trp (W) 4 0.9% Tyr (Y) 14 3.2% Val (V) 36 8.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 47 Total number of positively charged residues (Arg + Lys): 47 Atomic composition: Carbon C 2197 Hydrogen H 3477 Nitrogen N 575 Oxygen O 628 Sulfur S 23 Formula: C2197H3477N575O628S23 Total number of atoms: 6900 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 43360 Abs 0.1% (=1 g/l) 0.890, assuming all pairs of Cys residues form cystines Ext. coefficient 42860 Abs 0.1% (=1 g/l) 0.880, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.14 This classifies the protein as unstable. Aliphatic index: 96.77 Grand average of hydropathicity (GRAVY): 0.014