ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MANKVIQLQK IFQSSTKPLW WRHPRSALYL YPFYAIFAVA VVTPLLYIPN AIRGIKAKKA 

References and documentation are available.

Number of amino acids: 60

Molecular weight: 6932.37

Theoretical pI: 10.57

Amino acid composition: 
Ala (A)   8	 13.3%
Arg (R)   3	  5.0%
Asn (N)   2	  3.3%
Asp (D)   0	  0.0%
Cys (C)   0	  0.0%
Gln (Q)   3	  5.0%
Glu (E)   0	  0.0%
Gly (G)   1	  1.7%
His (H)   1	  1.7%
Ile (I)   6	 10.0%
Leu (L)   6	 10.0%
Lys (K)   6	 10.0%
Met (M)   1	  1.7%
Phe (F)   3	  5.0%
Pro (P)   5	  8.3%
Ser (S)   3	  5.0%
Thr (T)   2	  3.3%
Trp (W)   2	  3.3%
Tyr (Y)   4	  6.7%
Val (V)   4	  6.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 0
Total number of positively charged residues (Arg + Lys): 9

Atomic composition:

Carbon      C	       333
Hydrogen    H	       520
Nitrogen    N	        84
Oxygen      O	        75
Sulfur      S	         1

Formula: C333H520N84O75S1
Total number of atoms: 1013

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    16960
Abs 0.1% (=1 g/l)   2.446

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 48.97
This classifies the protein as unstable.



Aliphatic index: 110.67

Grand average of hydropathicity (GRAVY): 0.242