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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MANRIEQITV PDLGGASEVD VIEVLVKPGD TVAKEDGLIT LEGDKASMDV PSPLAGTIKE

70 80 90 100 110 120
LQVKVGDKVK EGDKILTLEM SAEEEKPAKE EKKESEKSEK LEEEGKKEKE EKSEPKEEKK

130 140 150 160 170 180
KATEIKEYEA EEVEGFGTSV HAGPAVRRIA REFGIDLTKI KGTGQKDRIL KEDVQKFVKE

190 200 210 220 230 240
QLKVAEGKSG IGFPPAPKID FKKFGAIEEK PLSKIKKATG VNLSRNWMTI PHVTQFGEAD

250 260 270 280 290 300
ITELQAFRQS QKEYAAKQNV RLTPLVFIIK AVVNALKEFP HFNASLDPTG EHLILKKYFH

310 320 330 340 350 360
IGVAVDTPEG LVVPVIRDAD KKGLFELAKE LGEVSEKARK KGLNMNDMQG GCFSISSLGG

370 380 390 400 410 420
IGGTAFTPII NAPEVVILGV SKMQWKPICN EAGDCKTRLM LPLSLSYDHR VIDGADGARF

430
IVYLAERLSD IRTLLL


References and documentation are available.

Number of amino acids: 436 Molecular weight: 47973.34 Theoretical pI: 5.93
Amino acid composition: 
Ala (A) 33 7.6% Arg (R) 15 3.4% Asn (N) 10 2.3% Asp (D) 23 5.3% Cys (C) 3 0.7% Gln (Q) 12 2.8% Glu (E) 50 11.5% Gly (G) 37 8.5% His (H) 6 1.4% Ile (I) 31 7.1% Leu (L) 37 8.5% Lys (K) 53 12.2% Met (M) 8 1.8% Phe (F) 16 3.7% Pro (P) 21 4.8% Ser (S) 21 4.8% Thr (T) 20 4.6% Trp (W) 2 0.5% Tyr (Y) 5 1.1% Val (V) 33 7.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 73 Total number of positively charged residues (Arg + Lys): 68 Atomic composition: Carbon C 2140 Hydrogen H 3490 Nitrogen N 570 Oxygen O 651 Sulfur S 11 Formula: C2140H3490N570O651S11 Total number of atoms: 6862 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 18575 Abs 0.1% (=1 g/l) 0.387, assuming all pairs of Cys residues form cystines Ext. coefficient 18450 Abs 0.1% (=1 g/l) 0.385, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.22 This classifies the protein as stable. Aliphatic index: 90.34 Grand average of hydropathicity (GRAVY): -0.385