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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MANRSEEAEY ENDSRRNHQD KKKEGVLDLV LKRPLRWLRM LIEELHWSFF FGVIIVYGVS

70 80 90 100 110 120
QGLGKGLSKV STQYYFKDEQ KIQPSQAQIY VGLIQIPWII KPLWGLLTDV VPVLGYRRRP

130 140 150 160 170 180
YFILAGFLAM ISMMVLWLHT NLHLALALSC LVAGSAGVAI ADVTIDACVT QCSISHPTLA

190 200 210 220 230 240
ADMQSLCGLC SSIGSLVGFS LSGVLVHLVG SKGVYGLLGV TAGLLVVVGM VLKESPSRSL

250 260 270 280 290 300
GRKHVNDKFL DAGSAIWKTF QYGEVWRPCL FMLLSAAVSL HIHEGMFYWY TDSKDGPSFS

310 320 330 340 350 360
KEAVGSIMSF GAIGSLVGIL LYQNFLKNFP FRNVVFWALS LSVLSGFLDL ILVLRINLKL

370 380 390 400 410 420
GLPDYFFIVV DEFVSHMISR IKWLPLLVLS SKLCPAGMEG TFFALLMSIE HIGHLVSSWG

430 440 450 460 470 480
GGVLLHALKV TRTQFDNLWL VIVIRSLLRV IPIGLVFLIP NVDSNSTILP AEMLTSRISE

490
GVDTEKIEMT ALISDEA


References and documentation are available.

Number of amino acids: 497 Molecular weight: 55027.90 Theoretical pI: 8.09
Amino acid composition: 
Ala (A) 28 5.6% Arg (R) 19 3.8% Asn (N) 12 2.4% Asp (D) 19 3.8% Cys (C) 7 1.4% Gln (Q) 13 2.6% Glu (E) 20 4.0% Gly (G) 41 8.2% His (H) 13 2.6% Ile (I) 36 7.2% Leu (L) 75 15.1% Lys (K) 22 4.4% Met (M) 15 3.0% Phe (F) 25 5.0% Pro (P) 17 3.4% Ser (S) 47 9.5% Thr (T) 16 3.2% Trp (W) 12 2.4% Tyr (Y) 13 2.6% Val (V) 47 9.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 39 Total number of positively charged residues (Arg + Lys): 41 Atomic composition: Carbon C 2540 Hydrogen H 4001 Nitrogen N 639 Oxygen O 677 Sulfur S 22 Formula: C2540H4001N639O677S22 Total number of atoms: 7879 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 85745 Abs 0.1% (=1 g/l) 1.558, assuming all pairs of Cys residues form cystines Ext. coefficient 85370 Abs 0.1% (=1 g/l) 1.551, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.82 This classifies the protein as stable. Aliphatic index: 120.16 Grand average of hydropathicity (GRAVY): 0.511