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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MANSLDRLRE HLKNGDKLVL KNNEGQSTDD ITKATMVETL SSDGSTQDSF PLNEETEIEI

70 80 90 100 110 120
DGSLVQLRII VHCWMNKDSS AADYLADCQN KQLTNVSFLQ RTDLINWLSG NTESSQYLKA

130 140 150 160 170 180
PGQKGETSDK VDIENKTLAG ELSTVKSTTS ASLENDSEVS DPVVVETMKH ERILVDHNSA

190 200 210 220 230 240
LRGAKPINFG YLIKDAELKL VQSIKGSLRG SKLPPGHKGA HGRISKTNGS SGGPRKDPII

250 260 270 280 290 300
LIPSAASSIL TVANIKQFLL ESKYVNPRNL PSVPNGLVNI EKNFERISRP IRFIIVDNTR

310 320 330 340 350 360
MFTKPEYWDR VVAIFTTGHT WQFNNYQWNS PQELFQRCKG YYFHFAGDSV PQHVQQWNVE

370 380 390
KVELDKNKRF KDVEVVRYFW HSLEKELISR GYR


References and documentation are available.

Number of amino acids: 393 Molecular weight: 44456.16 Theoretical pI: 7.72
Amino acid composition: 
Ala (A) 17 4.3% Arg (R) 20 5.1% Asn (N) 27 6.9% Asp (D) 23 5.9% Cys (C) 3 0.8% Gln (Q) 17 4.3% Glu (E) 26 6.6% Gly (G) 23 5.9% His (H) 10 2.5% Ile (I) 24 6.1% Leu (L) 35 8.9% Lys (K) 30 7.6% Met (M) 5 1.3% Phe (F) 14 3.6% Pro (P) 16 4.1% Ser (S) 37 9.4% Thr (T) 22 5.6% Trp (W) 7 1.8% Tyr (Y) 10 2.5% Val (V) 27 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 1967 Hydrogen H 3110 Nitrogen N 554 Oxygen O 605 Sulfur S 8 Formula: C1967H3110N554O605S8 Total number of atoms: 6244 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 53525 Abs 0.1% (=1 g/l) 1.204, assuming all pairs of Cys residues form cystines Ext. coefficient 53400 Abs 0.1% (=1 g/l) 1.201, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 34.12 This classifies the protein as stable. Aliphatic index: 82.80 Grand average of hydropathicity (GRAVY): -0.566