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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAPFRQDSIL IIYPRSQTTL VQFGLNEETF TVPELEIPTQ IYRTTRQDGS YTYHSTNKDN

70 80 90 100 110 120
KAELIKPIQN GEIIDISAFT QFLRLIFVSI LSDRANKNQD AFEAELSNIP LLLITHHSWS

130 140 150 160 170 180
QSDLEIITQY VFESLEINNL IQLPASLAAT YSMISLQNCC IIDVGTHHTD IIPIVDYAQL

190 200 210 220 230 240
DHLVSSIPMG GQSINDSLKK LLPQWDDDQI ESLKKSPIFE VLSDDAKKLS SFDFGNENED

250 260 270 280 290 300
EDEGTLNVAE IITSGRDTRE VLEERERGQK VKNVKNSDLE FNTFWDEKGN EIKVGKQRFQ

310 320 330 340 350 360
GCNNLIKNIS NRVGLTLDNI DDINKAKAVW ENIIIVGGTT SISGFKEALL GQLLKDHLII

370 380 390 400 410 420
EPEEEKSKRE EEAKSVLPAA TKKKSKFMTN STAFVPTIEY VQCPTVIKLA KYPDYFPEWK

430 440 450 460
KSGYSEIIFL GAQIVSKQIF THPKDTFYIT REKYNMKGPA ALWDVQF


References and documentation are available.

Number of amino acids: 467 Molecular weight: 53074.19 Theoretical pI: 5.03
Amino acid composition: 
Ala (A) 23 4.9% Arg (R) 14 3.0% Asn (N) 27 5.8% Asp (D) 30 6.4% Cys (C) 4 0.9% Gln (Q) 24 5.1% Glu (E) 38 8.1% Gly (G) 21 4.5% His (H) 8 1.7% Ile (I) 48 10.3% Leu (L) 41 8.8% Lys (K) 36 7.7% Met (M) 5 1.1% Phe (F) 22 4.7% Pro (P) 19 4.1% Ser (S) 36 7.7% Thr (T) 30 6.4% Trp (W) 6 1.3% Tyr (Y) 13 2.8% Val (V) 22 4.7% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 68 Total number of positively charged residues (Arg + Lys): 50 Atomic composition: Carbon C 2382 Hydrogen H 3746 Nitrogen N 618 Oxygen O 734 Sulfur S 9 Formula: C2382H3746N618O734S9 Total number of atoms: 7489 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 52620 Abs 0.1% (=1 g/l) 0.991, assuming all pairs of Cys residues form cystines Ext. coefficient 52370 Abs 0.1% (=1 g/l) 0.987, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 38.87 This classifies the protein as stable. Aliphatic index: 92.91 Grand average of hydropathicity (GRAVY): -0.363