ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAPGLTQTAD AMSTVTITKP SLPSVQDSDR AYVTFLAGNG DYVKGVVGLA KGLRKVKSAY 

        70         80         90        100        110        120 
PLVVAMLPDV PEEHRRILVD QGCIVREIEP VYPPENQTQF AMAYYVINYS KLRIWKFVEY 

       130        140        150        160        170        180 
SKMIYLDGDI QVYENIDHLF DLPDGYLYAV MDCFCEKTWS HTPQYKIRYC QQCPDKVQWP 

       190        200        210        220        230        240 
KAELGEPPAL YFNAGMFLYE PNLETYEDLL RTLKITPPTP FAEQDFLNMY FKKIYKPIPL 

       250        260        270        280        290        300 
VYNLVLAMLW RHPENVELGK VKVVHYCAAG SKPWRYTGKE ANMEREDIKM LVKKWWDIYD 

       310        320        330        340 
DESLDYKKPV TVVDTEVDLV NLKPFITALT EAGRLNYVTA PSAA 

References and documentation are available.

Number of amino acids: 344

Molecular weight: 39595.78

Theoretical pI: 5.54

Amino acid composition: 
Ala (A)  24	  7.0%
Arg (R)  12	  3.5%
Asn (N)  12	  3.5%
Asp (D)  22	  6.4%
Cys (C)   6	  1.7%
Gln (Q)  11	  3.2%
Glu (E)  22	  6.4%
Gly (G)  15	  4.4%
His (H)   5	  1.5%
Ile (I)  16	  4.7%
Leu (L)  32	  9.3%
Lys (K)  26	  7.6%
Met (M)  11	  3.2%
Phe (F)  11	  3.2%
Pro (P)  26	  7.6%
Ser (S)  11	  3.2%
Thr (T)  19	  5.5%
Trp (W)   7	  2.0%
Tyr (Y)  25	  7.3%
Val (V)  31	  9.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 44
Total number of positively charged residues (Arg + Lys): 38

Atomic composition:

Carbon      C	      1817
Hydrogen    H	      2782
Nitrogen    N	       446
Oxygen      O	       511
Sulfur      S	        17

Formula: C1817H2782N446O511S17
Total number of atoms: 5573

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    76125
Abs 0.1% (=1 g/l)   1.923, assuming all pairs of Cys residues form cystines


Ext. coefficient    75750
Abs 0.1% (=1 g/l)   1.913, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.98
This classifies the protein as stable.



Aliphatic index: 87.53

Grand average of hydropathicity (GRAVY): -0.235