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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAPKKHSGFM MFVNEWRNRN AEGRRMTLAQ AVSHCGTIWE KMNTQQRGPY NSGGKDANVA

70 80 90 100 110 120
QRAKRESSNG HGQVDKAQRE ATESLMDMKR TIERLVLNAK MSHDLENAKF VFVAFNYFTK

130 140 150 160 170 180
ALTTDVYVPA EFAACEYSLK EGIRSIYSTM IDPGQIIFGQ GSDALLHSST THDLPLPPNA

190 200 210 220 230 240
LGEKNMTKLY RNIVDYLSKC QGKGKTLVVF TPAENITMVK SCFRYLECDD DFRDGGEKIQ

250 260 270 280 290 300
VFDIQYLLFI LKKEVMNVAD LNDEKINKFA TDAFFKKDFF EFTAGIACQY HEDNDRTKYC

310 320 330 340 350 360
TQSMVTRWAY TFTDFMCGDL AITVQPGKHI PAQTKPNYLI ISSYASSLDH ESSFDSFYSL

370 380 390 400 410 420
PGSGVKKESQ PEACSLSSSR LSVASSSYKP IDHTSFAANL NEVSEFPSLG MRNSSKHHGI

430 440 450
AASAQREWNA RNLPTHSRLI RKVSDNDFSV NGADGKLKK


References and documentation are available.

Number of amino acids: 459 Molecular weight: 51601.32 Theoretical pI: 8.40
Amino acid composition: 
Ala (A) 37 8.1% Arg (R) 22 4.8% Asn (N) 26 5.7% Asp (D) 28 6.1% Cys (C) 9 2.0% Gln (Q) 17 3.7% Glu (E) 25 5.4% Gly (G) 26 5.7% His (H) 13 2.8% Ile (I) 21 4.6% Leu (L) 31 6.8% Lys (K) 35 7.6% Met (M) 15 3.3% Phe (F) 26 5.7% Pro (P) 16 3.5% Ser (S) 43 9.4% Thr (T) 26 5.7% Trp (W) 4 0.9% Tyr (Y) 16 3.5% Val (V) 23 5.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 53 Total number of positively charged residues (Arg + Lys): 57 Atomic composition: Carbon C 2273 Hydrogen H 3533 Nitrogen N 633 Oxygen O 694 Sulfur S 24 Formula: C2273H3533N633O694S24 Total number of atoms: 7157 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 46340 Abs 0.1% (=1 g/l) 0.898, assuming all pairs of Cys residues form cystines Ext. coefficient 45840 Abs 0.1% (=1 g/l) 0.888, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 36.57 This classifies the protein as stable. Aliphatic index: 66.78 Grand average of hydropathicity (GRAVY): -0.494