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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAPKRKSVKG GVEPKNKKVK TAIHQKEPNT LLSLEELTNL SKEIDESLKF NNLVPLLEQF

70 80 90 100 110 120
KLIKTKLIES IDPDVESTAR KLSLLLYRNF NKINDEIISN GNGAKSSASE DKKMIIKWLS

130 140 150 160 170 180
EKYTTFKDII YGFIEDKLAG STSLQLDLLD IILNFIRLES QRKSSTSQVV FFPTQSYKSL

190 200 210 220 230 240
TESILNSKNG EISFDGTTDN FIVLEFLDKF QKYWDLQFYF FNNLSEVLNE WKQEKSEKDL

250 260 270 280 290 300
QLIFANFLTV LRKGLLFNEK TLEEEPLWIA PNKEGKLPSS LYKHTLFKSQ FQKSVIAMLS

310 320 330 340 350 360
YPLLQEQYKS VLTILHKRII PYMSQPQSLM DFLTDCYDLT DDLIVPILAL NSLYELMKNY

370 380 390 400 410 420
NLEYPDFYSK LYSLLTPELL YTKYRSRFFR LCDLFLSSTH LSANLVASFI KKLARISLAA

430 440 450 460 470 480
SASGVVIIIP FIYNLLKRHP TCMIMLHKED TESGYQDPFN SEEKNPLHTE AIKSSLWELD

490 500 510 520 530 540
TLMTHYHPNV ATLAKIFGEP FRKPSYNMED FLDWSYNSLL QSEYDRKFKD KNSALEFEEF

550 560
DKVLDTSNSD SKSSLLEGWT LV


References and documentation are available.

Number of amino acids: 562 Molecular weight: 65200.98 Theoretical pI: 6.10
Amino acid composition: 
Ala (A) 20 3.6% Arg (R) 14 2.5% Asn (N) 32 5.7% Asp (D) 31 5.5% Cys (C) 3 0.5% Gln (Q) 18 3.2% Glu (E) 43 7.7% Gly (G) 14 2.5% His (H) 9 1.6% Ile (I) 36 6.4% Leu (L) 83 14.8% Lys (K) 55 9.8% Met (M) 10 1.8% Phe (F) 34 6.0% Pro (P) 22 3.9% Ser (S) 58 10.3% Thr (T) 30 5.3% Trp (W) 7 1.2% Tyr (Y) 24 4.3% Val (V) 19 3.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 74 Total number of positively charged residues (Arg + Lys): 69 Atomic composition: Carbon C 2984 Hydrogen H 4658 Nitrogen N 734 Oxygen O 873 Sulfur S 13 Formula: C2984H4658N734O873S13 Total number of atoms: 9262 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 74385 Abs 0.1% (=1 g/l) 1.141, assuming all pairs of Cys residues form cystines Ext. coefficient 74260 Abs 0.1% (=1 g/l) 1.139, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.18 This classifies the protein as unstable. Aliphatic index: 95.94 Grand average of hydropathicity (GRAVY): -0.304