Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAPNQRSRSL LQRHRGKVLI SLTGIAALFT TGSVVVFFVK RWLYKQQLRI TEQHFIKEQI

70 80 90 100 110 120
KRRFEQTQED SLYTIYELLP VWRMVLNEND LNLDSIVTQL KDQKNQLTRA KSSESRESSP

130 140 150 160 170 180
LKSKAELWNE LELKSLIKLV TVTYTVSSLI LLTRLQLNIL TRNEYLDSAI KLTMQQENCN

190 200 210 220 230 240
KLQNRFYNWV TSWWSDPEDK ADDAMVMAAK KSKKEGQEVY INEQAFLSLS WWILNKGWLS

250 260 270 280 290 300
YNEIITNQIE IEFDGIHPRD TLTLEEFSSR LTNIFRNTNS QIFQQNNNNL TSILLPKDSS

310 320 330 340 350 360
GQEFLLSQTL DADALTSFHS NTLVFNQLVN ELTQCIESTA TSIVLESLIN ESFHFIMNKV

370 380 390 400 410 420
GIKTIAKKKP GQEDQQQYQM AVFAMSMKDC CQEMLQTTAG SSHSGSVNEY LATLDSVQPL

430 440
DDLSASVYSN FGVSSSFSFK P


References and documentation are available.

Number of amino acids: 441 Molecular weight: 50675.59 Theoretical pI: 5.98
Amino acid composition: 
Ala (A) 20 4.5% Arg (R) 17 3.9% Asn (N) 30 6.8% Asp (D) 19 4.3% Cys (C) 4 0.9% Gln (Q) 33 7.5% Glu (E) 30 6.8% Gly (G) 12 2.7% His (H) 6 1.4% Ile (I) 27 6.1% Leu (L) 54 12.2% Lys (K) 28 6.3% Met (M) 10 2.3% Phe (F) 20 4.5% Pro (P) 9 2.0% Ser (S) 48 10.9% Thr (T) 31 7.0% Trp (W) 9 2.0% Tyr (Y) 11 2.5% Val (V) 23 5.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 45 Atomic composition: Carbon C 2255 Hydrogen H 3566 Nitrogen N 604 Oxygen O 693 Sulfur S 14 Formula: C2255H3566N604O693S14 Total number of atoms: 7132 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 66140 Abs 0.1% (=1 g/l) 1.305, assuming all pairs of Cys residues form cystines Ext. coefficient 65890 Abs 0.1% (=1 g/l) 1.300, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 45.29 This classifies the protein as unstable. Aliphatic index: 91.29 Grand average of hydropathicity (GRAVY): -0.350