ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAPPKKTVKK MDLTSFLNDD TFGSSWAEED VDLNKITIPI ETANANTIPL SELAHAKNNS 

        70         80         90        100        110        120 
NNTRSGGFGG SFGGRSRLDP ALGGGSSDRR EEYPVPDAPP YRAVINNIPW DITPEGVQAW 

       130        140        150        160        170        180 
VEDGLVKPEA VEEVVLPKNL RDPTRLKGNA FVTLKERADL VAVLKFNGTK LNERTVYVSV 

       190        200        210        220        230        240 
AAPRRGGGAD VDWSSARGSN FQGDGREDAP DLDWGAARGS NFRGPRRERE EVDIDWTAAR 

       250        260        270        280        290        300 
GSNFQGSSRP PRREREEVDI DWSAARGSNF QGSSRPPRRE REEPDIDWSA ARGSNFQSSS 

       310        320        330        340        350        360 
RPPRREREEP DIDWSAARGS NFQSSSRPPR REREKEEPAL DWGAARGAQF GKPQQTKNTY 

       370        380        390        400        410        420 
KDRSLTNKKT TDEQPKIQKS VYDVLRTEDD DEDEEAEKQN GDAKENKVDA AVEKLQDKTA 

       430 
QLTVEDGDNW EVVGKK 

References and documentation are available.

Number of amino acids: 436

Molecular weight: 48522.02

Theoretical pI: 5.17

Amino acid composition: 
Ala (A)  38	  8.7%
Arg (R)  42	  9.6%
Asn (N)  25	  5.7%
Asp (D)  39	  8.9%
Cys (C)   0	  0.0%
Gln (Q)  14	  3.2%
Glu (E)  40	  9.2%
Gly (G)  35	  8.0%
His (H)   1	  0.2%
Ile (I)  12	  2.8%
Leu (L)  21	  4.8%
Lys (K)  27	  6.2%
Met (M)   2	  0.5%
Phe (F)  13	  3.0%
Pro (P)  30	  6.9%
Ser (S)  34	  7.8%
Thr (T)  21	  4.8%
Trp (W)  11	  2.5%
Tyr (Y)   5	  1.1%
Val (V)  26	  6.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 79
Total number of positively charged residues (Arg + Lys): 69

Atomic composition:

Carbon      C	      2087
Hydrogen    H	      3283
Nitrogen    N	       641
Oxygen      O	       694
Sulfur      S	         2

Formula: C2087H3283N641O694S2
Total number of atoms: 6707

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    67950
Abs 0.1% (=1 g/l)   1.400

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 46.02
This classifies the protein as unstable.



Aliphatic index: 55.53

Grand average of hydropathicity (GRAVY): -1.099