ProtParam
User-provided sequence:
10 20 30 40 50 60
MAPSAQPLPV SVSDEKYANV KWEELAFKFV RTDYMYVAKC NHGESFQEGK ILPFADLQLN
70 80 90 100 110 120
PCAAVLQYGQ GLYEGLKAYR TEDGRILLFR PDQNGLRLQA GADRLYMPYP SVDQFVSAIK
130 140 150 160 170 180
QVALANKKWI PPPGKGTLYI RPILFGSGPI LGSFPIPETT FTAFACPVGR YHKDNSGLNL
190 200 210 220 230 240
KIEDQFRRAF PSGTGGVKSI TNYCPVWIPL AEAKKQGFSD ILFLDAATGK NIEELFAANV
250 260 270 280 290 300
FMLKGNVVST PTIAGTILPG VTRNCVMELC RDFGYQVEER TIPLVDFLDA DEAFCTGTAS
310 320 330 340 350
IVTSIASVTF KDKKTGFKTG EETLAAKLYE TLSDIQTGRV EDTKGWTVEI DRQG
References and
documentation are available.
Number of amino acids: 354
Molecular weight: 39018.71
Theoretical pI: 5.90
Total number of negatively charged residues (Asp + Glu): 40
Total number of positively charged residues (Arg + Lys): 38
Atomic composition:
Carbon C 1767
Hydrogen H 2746
Nitrogen N 456
Oxygen O 516
Sulfur S 12
Formula: C
1767H
2746N
456O
516S
12
Total number of atoms: 5497
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 41745
Abs 0.1% (=1 g/l) 1.070, assuming all pairs of Cys residues form cystines
Ext. coefficient 41370
Abs 0.1% (=1 g/l) 1.060, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 36.48
This classifies the protein as stable.
Aliphatic index: 83.50
Grand average of hydropathicity (GRAVY): -0.139