ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAQIQHQGQN ANGGVAVPGA AAAEAAAAAA GAAAAAAGAA QQGTTSLYVG DLDATVTDSQ 

        70         80         90        100        110        120 
LFEAFTQAGQ VVSVRVCRDM TTRRSLGYGY VNYATPQDAS RALNELNFMA LNGRAIRVMY 

       130        140        150        160        170        180 
SVRDPSLRKS GVGNIFIKNL DKSIDHKALH ETFSAFGPIL SCKVAVDPSG QSKGYGFVQY 

       190        200        210        220        230        240 
DTDEAAQGAI DKLNGMLLND KQVYVGPFVH KLQRDPSGEK VKFTNVYVKN LSESLSDEEL 

       250        260        270        280        290        300 
NKVFGEFGVT TSCVIMRDGE GKSKGFGFVN FENSDDAARA VDALNGKTFD DKEWFVGKAQ 

       310        320        330        340        350        360 
KKSERETELK QKFEQSLKEA ADKSQGSNLY VKNLDESVTD DKLREHFAPF GTITSCKVMR 

       370        380        390        400        410        420 
DPSGVSRGSG FVAFSTPEEA TRAITEMNGK MIVTKPLYVA LAQRKEDRKA RLQAQFSQMR 

       430        440        450        460        470        480 
PVNMPPAVGP RMQMYPPGGP PMGQQLFYGQ GPPAMIPQPG FGYQQQLVPG MRPGGSPMPN 

       490        500        510        520        530        540 
FFMPMMQQGQ QQQQQQQQQQ RPGGGRRGAL PQPQQPSPMM QQQMHPRGRM YRYPQRDVNT 

       550        560        570        580        590        600 
MPGPTQNMLS VPYDVSSGGG VHHRDSPTSQ PVPIVALATR LANAAPEQQR TMLGENLYPL 

       610        620        630        640        650        660 
VEQLEPESAA KVTGMLLEMD QTEVLHLLES PEALKAKVTE AMDVLRSVAQ QQAGGAADQL 

       670 
ASLSLGDNIV P 

References and documentation are available.

Number of amino acids: 671

Molecular weight: 72779.31

Theoretical pI: 7.13

Amino acid composition: 
Ala (A)  68	 10.1%
Arg (R)  34	  5.1%
Asn (N)  26	  3.9%
Asp (D)  34	  5.1%
Cys (C)   4	  0.6%
Gln (Q)  61	  9.1%
Glu (E)  34	  5.1%
Gly (G)  62	  9.2%
His (H)   9	  1.3%
Ile (I)  14	  2.1%
Leu (L)  47	  7.0%
Lys (K)  34	  5.1%
Met (M)  30	  4.5%
Phe (F)  26	  3.9%
Pro (P)  46	  6.9%
Ser (S)  43	  6.4%
Thr (T)  30	  4.5%
Trp (W)   1	  0.1%
Tyr (Y)  18	  2.7%
Val (V)  50	  7.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 68
Total number of positively charged residues (Arg + Lys): 68

Atomic composition:

Carbon      C	      3169
Hydrogen    H	      5023
Nitrogen    N	       913
Oxygen      O	       986
Sulfur      S	        34

Formula: C3169H5023N913O986S34
Total number of atoms: 10125

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    32570
Abs 0.1% (=1 g/l)   0.448, assuming all pairs of Cys residues form cystines


Ext. coefficient    32320
Abs 0.1% (=1 g/l)   0.444, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 43.47
This classifies the protein as unstable.



Aliphatic index: 67.20

Grand average of hydropathicity (GRAVY): -0.479