ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAQLYSSVKP TPMLKDELDI VIPTIRNLDF LEMWRPFFEQ YHLIIVQDGD PSKVINIPVG 

        70         80         90        100        110        120 
FDYELYNRND INRILGPKAS CISFKDSACR CFGYMVSKKK YIYTIDDDCF VAKDPTGKEI 

       130        140        150        160        170        180 
NALEQHIKNL LSPSTPHFFN TLYDPYRDGA DFVRGYPFSM REGAITAVSH GLWLNIPDYD 

       190        200        210        220        230        240 
APTQLVKPLE KNSRYVDAVM TIPKGTLFPM CGMNLAFDRE LIGPAMYFGL MGDGQPIGRY 

       250        260        270        280        290        300 
DDMWAGWCVK VICDHMGWGV KTGLPYIWHS KASNPFVNLK KEYNGIFWQE EAIPFFQSVT 

       310        320        330        340        350        360 
LPKECTSVQQ CYLELAKLVR EKLGKVDPYF ITLATGMVTW IEAWEELNSA EGTEAEAPKG 


KN 

References and documentation are available.

Number of amino acids: 362

Molecular weight: 41281.56

Theoretical pI: 5.39

Amino acid composition: 
Ala (A)  21	  5.8%
Arg (R)  12	  3.3%
Asn (N)  16	  4.4%
Asp (D)  24	  6.6%
Cys (C)   9	  2.5%
Gln (Q)  10	  2.8%
Glu (E)  21	  5.8%
Gly (G)  25	  6.9%
His (H)   6	  1.7%
Ile (I)  25	  6.9%
Leu (L)  29	  8.0%
Lys (K)  25	  6.9%
Met (M)  13	  3.6%
Phe (F)  19	  5.2%
Pro (P)  25	  6.9%
Ser (S)  17	  4.7%
Thr (T)  17	  4.7%
Trp (W)   9	  2.5%
Tyr (Y)  18	  5.0%
Val (V)  21	  5.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 45
Total number of positively charged residues (Arg + Lys): 37

Atomic composition:

Carbon      C	      1883
Hydrogen    H	      2858
Nitrogen    N	       470
Oxygen      O	       531
Sulfur      S	        22

Formula: C1883H2858N470O531S22
Total number of atoms: 5764

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    76820
Abs 0.1% (=1 g/l)   1.861, assuming all pairs of Cys residues form cystines


Ext. coefficient    76320
Abs 0.1% (=1 g/l)   1.849, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.67
This classifies the protein as stable.



Aliphatic index: 80.80

Grand average of hydropathicity (GRAVY): -0.213