ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAQRVTFRRR NPYNTRSNKI KVVKTPGGIL RAQHVKKLAT RPKCGDCGSA LQGISTLRPR 

        70         80         90        100        110        120 
QYATVSKTHK TVSRAYGGSR CANCVKERII RAFLIEEQKI VKKVVKEQTE AAKKSEKKAK 


K 

References and documentation are available.

Number of amino acids: 121

Molecular weight: 13639.08

Theoretical pI: 10.84

Amino acid composition: 
Ala (A)  11	  9.1%
Arg (R)  13	 10.7%
Asn (N)   4	  3.3%
Asp (D)   1	  0.8%
Cys (C)   4	  3.3%
Gln (Q)   6	  5.0%
Glu (E)   6	  5.0%
Gly (G)   7	  5.8%
His (H)   2	  1.7%
Ile (I)   7	  5.8%
Leu (L)   5	  4.1%
Lys (K)  19	 15.7%
Met (M)   1	  0.8%
Phe (F)   2	  1.7%
Pro (P)   4	  3.3%
Ser (S)   7	  5.8%
Thr (T)   9	  7.4%
Trp (W)   0	  0.0%
Tyr (Y)   3	  2.5%
Val (V)  10	  8.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 7
Total number of positively charged residues (Arg + Lys): 32

Atomic composition:

Carbon      C	       592
Hydrogen    H	      1017
Nitrogen    N	       193
Oxygen      O	       165
Sulfur      S	         5

Formula: C592H1017N193O165S5
Total number of atoms: 1972

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     4720
Abs 0.1% (=1 g/l)   0.346, assuming all pairs of Cys residues form cystines


Ext. coefficient     4470
Abs 0.1% (=1 g/l)   0.328, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 50.15
This classifies the protein as unstable.



Aliphatic index: 71.74

Grand average of hydropathicity (GRAVY): -0.774