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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MARARKGALV QCDPSIKALI LQIDAKMSDI VLEELDDTHL LVNPSKVEFV KHELNRLLSK

70
NIYNPMDEEE NQ


References and documentation are available.

Number of amino acids: 72 Molecular weight: 8232.49 Theoretical pI: 5.00
Amino acid composition: 
Ala (A) 5 6.9% Arg (R) 3 4.2% Asn (N) 5 6.9% Asp (D) 6 8.3% Cys (C) 1 1.4% Gln (Q) 3 4.2% Glu (E) 7 9.7% Gly (G) 1 1.4% His (H) 2 2.8% Ile (I) 5 6.9% Leu (L) 10 13.9% Lys (K) 6 8.3% Met (M) 3 4.2% Phe (F) 1 1.4% Pro (P) 3 4.2% Ser (S) 4 5.6% Thr (T) 1 1.4% Trp (W) 0 0.0% Tyr (Y) 1 1.4% Val (V) 5 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 13 Total number of positively charged residues (Arg + Lys): 9 Atomic composition: Carbon C 359 Hydrogen H 593 Nitrogen N 99 Oxygen O 113 Sulfur S 4 Formula: C359H593N99O113S4 Total number of atoms: 1168 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 1490 Abs 0.1% (=1 g/l) 0.181, assuming all pairs of Cys residues form cystines Ext. coefficient 1490 Abs 0.1% (=1 g/l) 0.181, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.79 This classifies the protein as unstable. Aliphatic index: 108.33 Grand average of hydropathicity (GRAVY): -0.357