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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MARKKIREYD SKRLLKEHLK RLANIDLQIR SAQVTESTDF TELTNQESWL SSTKLVVKPD

70 80 90 100 110 120
MLFGKRGKSG LVALKLDLAE VADFVKARLG TEVEMEGCKA PITTFIVEPF VPHDQEYYLS

130 140 150 160 170 180
IVSDRLGCTI SFSECGGIEI EENWDKVKTI FLPAEKSMTL EVCAPLIATL PLEVRAKIGN

190 200 210 220 230 240
FIMGAFAVFQ DLDFSFMEMN PFTLVDGEPF PLDMRGELDD TAAFKNFNKW GDIEFPLPFG

250 260 270 280 290 300
RVLSSTENFI HGLDEKTSAS LKFTVLNPKG RIWTMVAGGG ASVIYADTVG DLGYASELGN

310 320 330 340 350 360
YAEYSGAPNE EEVLQYARVV IDCATTDPDG RKRALLIGGG IANFTDVAAT FNGIIRALRE

370 380 390 400 410 420
KETRLKASRM HIYVRRGGPN YQTGLARMRA LGEELGVPLE VYGPEATMTG ICKRAIDCIM


LPDA


References and documentation are available.

Number of amino acids: 424 Molecular weight: 46945.98 Theoretical pI: 5.16
Amino acid composition: 
Ala (A) 36 8.5% Arg (R) 24 5.7% Asn (N) 14 3.3% Asp (D) 25 5.9% Cys (C) 7 1.7% Gln (Q) 7 1.7% Glu (E) 35 8.3% Gly (G) 35 8.3% His (H) 4 0.9% Ile (I) 26 6.1% Leu (L) 42 9.9% Lys (K) 25 5.9% Met (M) 13 3.1% Phe (F) 22 5.2% Pro (P) 19 4.5% Ser (S) 21 5.0% Thr (T) 27 6.4% Trp (W) 4 0.9% Tyr (Y) 11 2.6% Val (V) 27 6.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 60 Total number of positively charged residues (Arg + Lys): 49 Atomic composition: Carbon C 2098 Hydrogen H 3320 Nitrogen N 554 Oxygen O 625 Sulfur S 20 Formula: C2098H3320N554O625S20 Total number of atoms: 6617 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 38765 Abs 0.1% (=1 g/l) 0.826, assuming all pairs of Cys residues form cystines Ext. coefficient 38390 Abs 0.1% (=1 g/l) 0.818, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 36.59 This classifies the protein as stable. Aliphatic index: 89.50 Grand average of hydropathicity (GRAVY): -0.097