ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MARNVLYPLY QLGGPQLRVF RTNFFIQLVR PGTAQPEDTV QFRIPMEMTR VDLRNYLEQI 

        70         80         90        100        110        120 
YNVPVAAVRT RVQHGSNRRR DHKNVRIKKP DYKVAYVQLA HGQTFTFPDL FPEKEPTSPD 

       130        140 
PLEEELPQQR QSSDPRCPGI PSWFGL 

References and documentation are available.

Number of amino acids: 146

Molecular weight: 17050.49

Theoretical pI: 9.60

Amino acid composition: 
Ala (A)   6	  4.1%
Arg (R)  15	 10.3%
Asn (N)   6	  4.1%
Asp (D)   7	  4.8%
Cys (C)   1	  0.7%
Gln (Q)  12	  8.2%
Glu (E)   8	  5.5%
Gly (G)   7	  4.8%
His (H)   3	  2.1%
Ile (I)   5	  3.4%
Leu (L)  12	  8.2%
Lys (K)   5	  3.4%
Met (M)   3	  2.1%
Phe (F)   8	  5.5%
Pro (P)  16	 11.0%
Ser (S)   5	  3.4%
Thr (T)   8	  5.5%
Trp (W)   1	  0.7%
Tyr (Y)   6	  4.1%
Val (V)  12	  8.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 15
Total number of positively charged residues (Arg + Lys): 20

Atomic composition:

Carbon      C	       766
Hydrogen    H	      1193
Nitrogen    N	       221
Oxygen      O	       214
Sulfur      S	         4

Formula: C766H1193N221O214S4
Total number of atoms: 2398

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    14440
Abs 0.1% (=1 g/l)   0.847, assuming all pairs of Cys residues form cystines


Ext. coefficient    14440
Abs 0.1% (=1 g/l)   0.847, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 50.59
This classifies the protein as unstable.



Aliphatic index: 73.36

Grand average of hydropathicity (GRAVY): -0.677