ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MARTITFDIP SQYKLVDLIG EGAYGTVCSA IHKPSGIKVA IKKIQPFSKK LFVTRTIREI 

        70         80         90        100        110        120 
KLLRYFHEHE NIISILDKVR PVSIDKLNAV YLVEELMETD LQKVINNQNS GFSTLSDDHV 

       130        140        150        160        170        180 
QYFTYQILRA LKSIHSAQVI HRDIKPSNLL LNSNCDLKVC DFGLARCLAS SSDSRETLVG 

       190        200        210        220        230        240 
FMTEYVATRW YRAPEIMLTF QEYTTAMDIW SCGCILAEMV SGKPLFPGRD YHHQLWLILE 

       250        260        270        280        290        300 
VLGTPSFEDF NQIKSKRAKE YIANLPMRPP LPWETVWSKT DLNPDMIDLL DKMLQFNPDK 

       310        320        330        340        350        360 
RISAAEALRH PYLAMYHDPS DEPEYPPLNL DDEFWKLDNK IMRPEEEEEV PIEMLKDMLY 


DELMKTME 

References and documentation are available.

Number of amino acids: 368

Molecular weight: 42692.30

Theoretical pI: 5.39

Amino acid composition: 
Ala (A)  19	  5.2%
Arg (R)  17	  4.6%
Asn (N)  14	  3.8%
Asp (D)  26	  7.1%
Cys (C)   6	  1.6%
Gln (Q)  11	  3.0%
Glu (E)  28	  7.6%
Gly (G)  11	  3.0%
His (H)  10	  2.7%
Ile (I)  28	  7.6%
Leu (L)  41	 11.1%
Lys (K)  25	  6.8%
Met (M)  15	  4.1%
Phe (F)  14	  3.8%
Pro (P)  22	  6.0%
Ser (S)  24	  6.5%
Thr (T)  18	  4.9%
Trp (W)   6	  1.6%
Tyr (Y)  15	  4.1%
Val (V)  18	  4.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 54
Total number of positively charged residues (Arg + Lys): 42

Atomic composition:

Carbon      C	      1924
Hydrogen    H	      3009
Nitrogen    N	       495
Oxygen      O	       559
Sulfur      S	        21

Formula: C1924H3009N495O559S21
Total number of atoms: 6008

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    55725
Abs 0.1% (=1 g/l)   1.305, assuming all pairs of Cys residues form cystines


Ext. coefficient    55350
Abs 0.1% (=1 g/l)   1.296, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.02
This classifies the protein as unstable.



Aliphatic index: 92.47

Grand average of hydropathicity (GRAVY): -0.284