ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MASHIVGYPR MGPKRELKFA LESFWDGKST AEDLQKVSAD LRSSIWKQMS AAGTKFIPSN 

        70         80         90        100        110        120 
TFAHYDQVLD TTAMLGAVPP RYGYTGGEIG LDVYFSMARG NASVPAMEMT KWFDTNYHYI 

       130        140        150        160        170        180 
VPELGPEVNF SYASHKAVNE YKEAKALGVD TVPVLVGPVS YLLLSKAAKG VDKSFELLSL 

       190        200        210        220        230        240 
LPKILPIYKE VITELKAAGA TWIQLDEPVL VMDLEGQKLQ AFTGAYAELE STLSGLNVLV 

       250        260        270        280        290        300 
ETYFADIPAE AYKTLTSLKG VTAFGFDLVR GTKTLDLVKA GFPEGKYLFA GVVDGRNIWA 

       310        320        330        340        350        360 
NDFAASLSTL QALEGIVGKD KLVVSTSCSL LHTAVDLINE TKLDDEIKSW LAFAAQKVVE 

       370        380        390        400        410        420 
VNALAKALAG QKDEALFSAN AAALASRRSS PRVTNEGVQK AAAALKGSDH RRATNVSARL 

       430        440        450        460        470        480 
DAQQKKLNLP ILPTTTIGSF PQTVELRRVR REYKAKKVSE EDYVKAIKEE IKKVVDLQEE 

       490        500        510        520        530        540 
LDIDVLVHGE PERNDMVEYF GEQLSGFAFT ANGWVQSYGS RCVKPPVIYG DVSRPKAMTV 

       550        560        570        580        590        600 
FWSAMAQSMT SRPMKGMLTG PVTILNWSFV RNDQPRHETC YQIALAIKDE VEDLEKGGIG 

       610        620        630        640        650        660 
VIQIDEAALR EGLPLRKSEH AFYLDWAVHS FRITNCGVQD STQIHTHMCY SHFNDIIHSI 

       670        680        690        700        710        720 
IDMDADVITI ENSRSDEKLL SVFREGVKYG AGIGPGVYDI HSPRIPSSEE IADRVNKMLA 

       730        740        750        760 
VLEQNILWVN PDCGLKTRKY TEVKPALKNM VDAAKLIRSQ LASAK 

References and documentation are available.

Number of amino acids: 765

Molecular weight: 84356.64

Theoretical pI: 6.09

Amino acid composition: 
Ala (A)  77	 10.1%
Arg (R)  32	  4.2%
Asn (N)  25	  3.3%
Asp (D)  44	  5.8%
Cys (C)   6	  0.8%
Gln (Q)  24	  3.1%
Glu (E)  51	  6.7%
Gly (G)  50	  6.5%
His (H)  15	  2.0%
Ile (I)  40	  5.2%
Leu (L)  73	  9.5%
Lys (K)  55	  7.2%
Met (M)  18	  2.4%
Phe (F)  27	  3.5%
Pro (P)  32	  4.2%
Ser (S)  54	  7.1%
Thr (T)  41	  5.4%
Trp (W)  11	  1.4%
Tyr (Y)  26	  3.4%
Val (V)  64	  8.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 95
Total number of positively charged residues (Arg + Lys): 87

Atomic composition:

Carbon      C	      3784
Hydrogen    H	      5984
Nitrogen    N	      1006
Oxygen      O	      1126
Sulfur      S	        24

Formula: C3784H5984N1006O1126S24
Total number of atoms: 11924

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    99615
Abs 0.1% (=1 g/l)   1.181, assuming all pairs of Cys residues form cystines


Ext. coefficient    99240
Abs 0.1% (=1 g/l)   1.176, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.29
This classifies the protein as stable.



Aliphatic index: 91.93

Grand average of hydropathicity (GRAVY): -0.141