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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MASIVVNVHD YGTWVEDGAR VQCTFCDKRM NDFNRLKYHL GNVCKDVTPC SQVPLPIREA

70 80 90 100 110 120
FFKMVMEQRY PDRKRGRSNK GFTASETAAE AEKLAQMDVA QFFYEHGVDF SAVDSTSFKK

130 140 150 160 170 180
MMMIKTVGGE GGGQMIPDSR DLNGWMFQEA LKKVQDRVKE IKASWEITGC SILFDAWIGP

190 200 210 220 230 240
KGRDLVTFVA DCPAGAVYLK SADVSDIKTD VTALTSLVNG IVEEVGVRNV TQIIACSTSG

250 260 270 280 290 300
WVGDLGKQLA GQVFWSVSLS YCLKLMLVEI GKMYSFEDIF EKVKLLLDLI NNNPSFLYVF

310 320 330 340 350 360
RENSHKVDVS SECEFVMPYL TLEHIYWVRR AGLFASPEWK KEQGIAISSF VNDSTFWESL

370 380 390 400 410 420
DKIVGSTSSL VHGWLWFSRG SKHVAYAYHF IESIKKNVAW TFKYERQFYE PTWNVIDDVW

430 440 450 460 470 480
HNNHNPLHAA GYFLNPMAYY SDDFHTYQHV YTGLAFSLVH LVKEPHLQVK IGTQLDVYRY

490 500 510 520 530 540
GRGCFMKASQ AGQLNGVSPV NWWTQKANQY PELQNLAVKI LSQTSEGASR YKLKRSVAEK

550 560 570
LLLTEGMSHC ERKHLEELAV VHYNLQLQSC KA


References and documentation are available.

Number of amino acids: 572 Molecular weight: 65104.47 Theoretical pI: 7.00
Amino acid composition: 
Ala (A) 38 6.6% Arg (R) 22 3.8% Asn (N) 24 4.2% Asp (D) 29 5.1% Cys (C) 12 2.1% Gln (Q) 24 4.2% Glu (E) 34 5.9% Gly (G) 37 6.5% His (H) 18 3.1% Ile (I) 24 4.2% Leu (L) 47 8.2% Lys (K) 40 7.0% Met (M) 16 2.8% Phe (F) 29 5.1% Pro (P) 16 2.8% Ser (S) 44 7.7% Thr (T) 25 4.4% Trp (W) 16 2.8% Tyr (Y) 24 4.2% Val (V) 53 9.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 63 Total number of positively charged residues (Arg + Lys): 62 Atomic composition: Carbon C 2942 Hydrogen H 4498 Nitrogen N 778 Oxygen O 840 Sulfur S 28 Formula: C2942H4498N778O840S28 Total number of atoms: 9086 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 124510 Abs 0.1% (=1 g/l) 1.912, assuming all pairs of Cys residues form cystines Ext. coefficient 123760 Abs 0.1% (=1 g/l) 1.901, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 33.53 This classifies the protein as stable. Aliphatic index: 81.92 Grand average of hydropathicity (GRAVY): -0.211