ProtParam
User-provided sequence:
10 20 30 40 50 60
MASLTRAVTR LAIAGRQAVR TIATTTPVSG HGDDIMEKWP ADKFDNHFIN YLNRPEIDGW
70 80 90 100 110 120
EVRKALSELH DYDVIPDPKV VEAALRACRR VNDFALAVRF LEAIKIKCGA QKNRDTVYAY
130 140 150 160 170
IVKQVEPVLK ELGIDTPEQL GYGEPEFFVP EPEYWWEKKW YKDYGYDKHP NIQI
References and
documentation are available.
Number of amino acids: 174
Molecular weight: 20110.93
Theoretical pI: 5.84
Total number of negatively charged residues (Asp + Glu): 27
Total number of positively charged residues (Arg + Lys): 24
Atomic composition:
Carbon C 915
Hydrogen H 1404
Nitrogen N 244
Oxygen O 260
Sulfur S 4
Formula: C
915H
1404N
244O
260S
4
Total number of atoms: 2827
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 41035
Abs 0.1% (=1 g/l) 2.040, assuming all pairs of Cys residues form cystines
Ext. coefficient 40910
Abs 0.1% (=1 g/l) 2.034, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 31.25
This classifies the protein as stable.
Aliphatic index: 84.08
Grand average of hydropathicity (GRAVY): -0.474