ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MASMMFTDCS STTTSRLIHL NRSSGTFLLR QCVGQLRLQT TASGRGCCIR SSSSPISSIS 

        70         80         90        100        110        120 
ADTKSEGGAI VIDGKAVAKK IRDEITIEVS RMKESIGVIP GLAVILVGDR KDSATYVRNK 

       130        140        150        160        170        180 
KKACDSVGIK SFEVRLAEDS SEEEVLKSVS GFNDDPSVHG ILVQLPLPSH MDEQNILNAV 

       190        200        210        220        230        240 
SIEKDVDGFH PLNIGRLAMR GREPLFVPCT PKGCIELLHR YNIEIKGKRA VVIGRSNIVG 

       250        260        270        280        290        300 
MPAALLLQRE DATVSIIHSR TKNPEEITRE ADIIISAVGQ PNMVRGSWIK PGAVLIDVGI 

       310        320        330        340        350        360 
NPVEDPSAAR GYRLVGDICY EEASKVASAI TPVPGGVGPM TIAMLLSNTL TSAKRIHNFQ 

References and documentation are available.

Number of amino acids: 360

Molecular weight: 38741.72

Theoretical pI: 8.58

Amino acid composition: 
Ala (A)  26	  7.2%
Arg (R)  24	  6.7%
Asn (N)  13	  3.6%
Asp (D)  18	  5.0%
Cys (C)   8	  2.2%
Gln (Q)   8	  2.2%
Glu (E)  21	  5.8%
Gly (G)  29	  8.1%
His (H)   7	  1.9%
Ile (I)  35	  9.7%
Leu (L)  27	  7.5%
Lys (K)  19	  5.3%
Met (M)  10	  2.8%
Phe (F)   7	  1.9%
Pro (P)  18	  5.0%
Ser (S)  37	 10.3%
Thr (T)  18	  5.0%
Trp (W)   1	  0.3%
Tyr (Y)   4	  1.1%
Val (V)  30	  8.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 43

Atomic composition:

Carbon      C	      1684
Hydrogen    H	      2791
Nitrogen    N	       487
Oxygen      O	       519
Sulfur      S	        18

Formula: C1684H2791N487O519S18
Total number of atoms: 5499

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    11960
Abs 0.1% (=1 g/l)   0.309, assuming all pairs of Cys residues form cystines


Ext. coefficient    11460
Abs 0.1% (=1 g/l)   0.296, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.83
This classifies the protein as unstable.



Aliphatic index: 98.56

Grand average of hydropathicity (GRAVY): -0.033