ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MASSQGRRRR PGTVVPGEAA ETDSELSASS SEEELYLGPS GPTRGRPTGL RVAGEAAETD 

        70         80         90        100        110        120 
SEPEPEPRVA PGDLPPLVVQ RDAVEAWGTE ETPVLAPARS LLQLRLAESQ TRLDHDVAAA 

       130        140        150        160        170        180 
VSGVYRRAGR DVAALAGRLA AAQAIGLAAA HSVRLARGDL CALAERLDIV AGCRLLPDIR 

       190 
GVPGIEPEQD PGPRA 

References and documentation are available.

Number of amino acids: 195

Molecular weight: 20300.74

Theoretical pI: 4.99

Amino acid composition: 
Ala (A)  32	 16.4%
Arg (R)  22	 11.3%
Asn (N)   0	  0.0%
Asp (D)  11	  5.6%
Cys (C)   2	  1.0%
Gln (Q)   6	  3.1%
Glu (E)  18	  9.2%
Gly (G)  19	  9.7%
His (H)   2	  1.0%
Ile (I)   4	  2.1%
Leu (L)  21	 10.8%
Lys (K)   0	  0.0%
Met (M)   1	  0.5%
Phe (F)   0	  0.0%
Pro (P)  18	  9.2%
Ser (S)  13	  6.7%
Thr (T)   8	  4.1%
Trp (W)   1	  0.5%
Tyr (Y)   2	  1.0%
Val (V)  15	  7.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 29
Total number of positively charged residues (Arg + Lys): 22

Atomic composition:

Carbon      C	       868
Hydrogen    H	      1430
Nitrogen    N	       272
Oxygen      O	       283
Sulfur      S	         3

Formula: C868H1430N272O283S3
Total number of atoms: 2856

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     8605
Abs 0.1% (=1 g/l)   0.424, assuming all pairs of Cys residues form cystines


Ext. coefficient     8480
Abs 0.1% (=1 g/l)   0.418, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 60.17
This classifies the protein as unstable.



Aliphatic index: 88.72

Grand average of hydropathicity (GRAVY): -0.300