ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MASSSLTSKS ILGSTKLGSS SLPSELRRLS SPAVQISLRT QTRKNFQIQA TGSSYGTHFR 

        70         80         90        100        110        120 
VSTFGESHGG GVGCIIDGCP PRIPLTESDL QFDLDRRRPG QSRITTPRKE TDTCRISSGV 

       130        140        150        160        170        180 
SEGMTTGTPI HVFVPNTDQR GLDYSEMSVA YRPSHADATY DMKYGVRSVQ GGGRSSARET 

       190        200        210        220        230        240 
IGRVAPGALA KKILKQFAGT EILAYVSQVH HVVLPEELVD HENLTLEQIE NNIVRCPNPE 

       250        260        270        280        290        300 
YAEKMIAAID AVRTKGNSVG GVVTCIVRNA PRGLGTPVFD KLEAELAKAC MSLPATKGFE 

       310        320        330        340        350        360 
FGSGFAGTFL TGLEHNDEFY TDENGRIRTR TNRSGGIQGG ISNGEIINMR VAFKPTSTIG 

       370        380        390        400        410        420 
RKQNTVTRDK VETEMIARGR HDPCVVPRAV PMVEAMVALV LVDQLMAQYA QCHLFPINPE 

       430 
LQEPLQIEQP QNATAL 

References and documentation are available.

Number of amino acids: 436

Molecular weight: 47317.69

Theoretical pI: 8.37

Amino acid composition: 
Ala (A)  31	  7.1%
Arg (R)  32	  7.3%
Asn (N)  16	  3.7%
Asp (D)  17	  3.9%
Cys (C)   8	  1.8%
Gln (Q)  20	  4.6%
Glu (E)  28	  6.4%
Gly (G)  40	  9.2%
His (H)  10	  2.3%
Ile (I)  26	  6.0%
Leu (L)  31	  7.1%
Lys (K)  16	  3.7%
Met (M)  11	  2.5%
Phe (F)  14	  3.2%
Pro (P)  25	  5.7%
Ser (S)  35	  8.0%
Thr (T)  35	  8.0%
Trp (W)   0	  0.0%
Tyr (Y)   9	  2.1%
Val (V)  32	  7.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 45
Total number of positively charged residues (Arg + Lys): 48

Atomic composition:

Carbon      C	      2051
Hydrogen    H	      3316
Nitrogen    N	       604
Oxygen      O	       642
Sulfur      S	        19

Formula: C2051H3316N604O642S19
Total number of atoms: 6632

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    13910
Abs 0.1% (=1 g/l)   0.294, assuming all pairs of Cys residues form cystines


Ext. coefficient    13410
Abs 0.1% (=1 g/l)   0.283, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 48.03
This classifies the protein as unstable.



Aliphatic index: 79.38

Grand average of hydropathicity (GRAVY): -0.314