ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MASSSNIKHR LWLDGCMDFF HYGHSNAILQ AKQLGETLVI GIHSDEEITL NKGPPVMTLE 

        70         80         90        100        110        120 
ERCLSANTCK WVDEVVPSAP YVFDLEWMRR YGCQYVVHGD DISTDANGDD CYRFAKAADQ 

       130        140        150        160        170        180 
YLEVKRTEGV STTELLDRLL SSVPLEIYST PVSVLSSQID LLRRFATDSD GLTPFTDVFI 

       190        200        210        220        230        240 
YNTEKPETLI SGTTLLRLNP EKNIIYIDGD WDLFTEKHIS ALELCTRMFP GIPIMAGIFA 

       250        260        270        280        290        300 
DEKCFEKPML NLLERILNLL QCKYISSILV GPPPASLFAS SKYIKLCFDE QISKVYYPIF 

       310        320        330        340        350        360 
STDVSIPALD ISLSNTPNNS FYKFDKLGSD LIKQRVMLRR QHYEERQRRK MGKNATEQTT 


IKTYA 

References and documentation are available.

Number of amino acids: 365

Molecular weight: 41556.61

Theoretical pI: 5.39

Amino acid composition: 
Ala (A)  18	  4.9%
Arg (R)  18	  4.9%
Asn (N)  14	  3.8%
Asp (D)  25	  6.8%
Cys (C)   9	  2.5%
Gln (Q)  11	  3.0%
Glu (E)  23	  6.3%
Gly (G)  17	  4.7%
His (H)   7	  1.9%
Ile (I)  27	  7.4%
Leu (L)  40	 11.0%
Lys (K)  21	  5.8%
Met (M)   9	  2.5%
Phe (F)  16	  4.4%
Pro (P)  18	  4.9%
Ser (S)  30	  8.2%
Thr (T)  24	  6.6%
Trp (W)   4	  1.1%
Tyr (Y)  16	  4.4%
Val (V)  18	  4.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 48
Total number of positively charged residues (Arg + Lys): 39

Atomic composition:

Carbon      C	      1862
Hydrogen    H	      2915
Nitrogen    N	       483
Oxygen      O	       557
Sulfur      S	        18

Formula: C1862H2915N483O557S18
Total number of atoms: 5835

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    46340
Abs 0.1% (=1 g/l)   1.115, assuming all pairs of Cys residues form cystines


Ext. coefficient    45840
Abs 0.1% (=1 g/l)   1.103, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.05
This classifies the protein as unstable.



Aliphatic index: 90.82

Grand average of hydropathicity (GRAVY): -0.207