ProtParam
User-provided sequence:
10 20 30 40 50 60
MASSSSLSLS FPSSSLSRTW DYDVFPSFHG EDVRKAFLSQ ILKKEFGRKA INFFVDHEME
70 80 90 100 110 120
RGEFIGPVLK QAIKGSKIAL VLLSKNYASS WCCLDELVEI MKKESGQTVI TIFYEVDPNE
130 140 150 160 170
VKKQTGDFGK AFKETCQGKT EEKVQTWRKA LEGVGLATIA GFHSSNWFVF FI
References and
documentation are available.
Number of amino acids: 172
Molecular weight: 19412.26
Theoretical pI: 7.69
Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 22
Atomic composition:
Carbon C 885
Hydrogen H 1362
Nitrogen N 224
Oxygen O 255
Sulfur S 6
Formula: C
885H
1362N
224O
255S
6
Total number of atoms: 2732
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 26595
Abs 0.1% (=1 g/l) 1.370, assuming all pairs of Cys residues form cystines
Ext. coefficient 26470
Abs 0.1% (=1 g/l) 1.364, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 28.11
This classifies the protein as stable.
Aliphatic index: 78.20
Grand average of hydropathicity (GRAVY): -0.165