ProtParam
User-provided sequence:
10 20 30 40 50 60
MASTANMISQ LKKLSIAEPA VAKDSHPDVN IVDLMRNYIS QELSKISGVD SSLIFPALEW
70 80 90 100 110 120
TNTMERGDLL IPIPRLRIKG ANPKDLAVQW AEKFPCGDFL EKVEANGPFI QFFFNPQFLA
130 140 150 160 170 180
KLVIPDILTR KEDYGSCKLV ENKKVIIEFS SPNIAKPFHA GHLRSTIIGG FLANLYEKLG
190 200 210 220 230 240
WEVIRMNYLG DWGKQFGLLA VGFERYGNEE ALVKDPIHHL FDVYVRINKD IEEEGDSIPL
250 260 270 280 290 300
EQSTNGKARE YFKRMEDGDE EALKIWKRFR EFSIEKYIDT YARLNIKYDV YSGESQVSKE
310 320 330 340 350 360
SMLKAIDLFK EKGLTHEDKG AVLIDLTKFN KKLGKAIVQK SDGTTLYLTR DVGAAMDRYE
370 380 390 400 410 420
KYHFDKMIYV IASQQDLHAA QFFEILKQMG FEWAKDLQHV NFGMVQGMST RKGTVVFLDN
430 440 450 460 470 480
ILEETKEKMH EVMKKNENKY AQIEHPEEVA DLVGISAVMI QDMQGKRINN YEFKWERMLS
490 500 510 520 530 540
FEGDTGPYLQ YAHSRLRSVE RNASGITQEK WINADFSLLK EPAAKLLIRL LGQYPDVLRN
550 560 570 580 590 600
AIKTHEPTTV VTYLFKLTHQ VSSCYDVLWV AGQTEELATA RLALYGAARQ VLYNGMRLLG
LTPVERM
References and
documentation are available.
Number of amino acids: 607
Molecular weight: 69524.99
Theoretical pI: 6.33
Total number of negatively charged residues (Asp + Glu): 84
Total number of positively charged residues (Arg + Lys): 79
Atomic composition:
Carbon C 3143
Hydrogen H 4923
Nitrogen N 829
Oxygen O 906
Sulfur S 22
Formula: C
3143H
4923N
829O
906S
22
Total number of atoms: 9823
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 85385
Abs 0.1% (=1 g/l) 1.228, assuming all pairs of Cys residues form cystines
Ext. coefficient 85260
Abs 0.1% (=1 g/l) 1.226, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 33.22
This classifies the protein as stable.
Aliphatic index: 90.30
Grand average of hydropathicity (GRAVY): -0.319