ProtParam
User-provided sequence:
10 20 30 40 50 60
MASTTCAREV HYRGVRKRPW GRYAAEIRDP WKKTRVWLGT FDTPEEAALA YDGAARFLRG
70 80 90 100 110 120
IKAKTNFPSP LSLDLNHLPS APSAATAAAN NQPHQHQQLW FAAPPPVPPS SDHHHQHHRI
130 140 150 160 170 180
FLRTGVLNDK TSDYSSTEAP LYFTSSPNTA TSSPGYQVVG FPMMNSSPSP VTVRRGLAID
LNEPPPLWL
References and
documentation are available.
Number of amino acids: 189
Molecular weight: 20946.57
Theoretical pI: 9.56
Total number of negatively charged residues (Asp + Glu): 14
Total number of positively charged residues (Arg + Lys): 19
Atomic composition:
Carbon C 939
Hydrogen H 1429
Nitrogen N 271
Oxygen O 269
Sulfur S 4
Formula: C
939H
1429N
271O
269S
4
Total number of atoms: 2912
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 36440
Abs 0.1% (=1 g/l) 1.740, assuming all pairs of Cys residues form cystines
Ext. coefficient 36440
Abs 0.1% (=1 g/l) 1.740, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 60.46
This classifies the protein as unstable.
Aliphatic index: 64.13
Grand average of hydropathicity (GRAVY): -0.554