ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATESSESEE EGKISGGNYK LIIDDDLREM GKNAAWSVSS CKPGNGVTTL RDDNLETYWQ 

        70         80         90        100        110        120 
SDGLQPHLIN IQFQKKVKLQ LVVLYVDFKL DESYTPSKIS IRAGDGFHNL KEIKSVELVK 

       130        140        150        160        170        180 
PTGWVCLSLS GTDPRETFVN TFMLQIAILS NHLNGRDTHI RQIKVYGPRP NPIPHQPFQF 

       190 
TSMEFLTYST LR 

References and documentation are available.

Number of amino acids: 192

Molecular weight: 21749.71

Theoretical pI: 6.21

Amino acid composition: 
Ala (A)   5	  2.6%
Arg (R)   8	  4.2%
Asn (N)  10	  5.2%
Asp (D)  11	  5.7%
Cys (C)   2	  1.0%
Gln (Q)   9	  4.7%
Glu (E)  12	  6.2%
Gly (G)  13	  6.8%
His (H)   5	  2.6%
Ile (I)  13	  6.8%
Leu (L)  19	  9.9%
Lys (K)  13	  6.8%
Met (M)   4	  2.1%
Phe (F)   8	  4.2%
Pro (P)  10	  5.2%
Ser (S)  17	  8.9%
Thr (T)  13	  6.8%
Trp (W)   3	  1.6%
Tyr (Y)   6	  3.1%
Val (V)  11	  5.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 21

Atomic composition:

Carbon      C	       971
Hydrogen    H	      1523
Nitrogen    N	       261
Oxygen      O	       294
Sulfur      S	         6

Formula: C971H1523N261O294S6
Total number of atoms: 3055

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    25565
Abs 0.1% (=1 g/l)   1.175, assuming all pairs of Cys residues form cystines


Ext. coefficient    25440
Abs 0.1% (=1 g/l)   1.170, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.03
This classifies the protein as stable.



Aliphatic index: 84.22

Grand average of hydropathicity (GRAVY): -0.433