ProtParam
User-provided sequence:
10 20 30 40 50 60
MATESSSPSS VRKVVVHLRA TGGAPILKQS KFKIPGTDKF AKVIDFLRRQ LHSDSLFVYV
70 80 90
NSAFSPNPDE SVIDLYNNFG FDGKLVVNYA CSMAWG
References and
documentation are available.
Number of amino acids: 96
Molecular weight: 10571.09
Theoretical pI: 9.21
Total number of negatively charged residues (Asp + Glu): 8
Total number of positively charged residues (Arg + Lys): 11
Atomic composition:
Carbon C 478
Hydrogen H 741
Nitrogen N 127
Oxygen O 138
Sulfur S 3
Formula: C
478H
741N
127O
138S
3
Total number of atoms: 1487
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 9970
Abs 0.1% (=1 g/l) 0.943, assuming all pairs of Cys residues form cystines
Ext. coefficient 9970
Abs 0.1% (=1 g/l) 0.943, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 54.32
This classifies the protein as unstable.
Aliphatic index: 82.19
Grand average of hydropathicity (GRAVY): -0.062