ProtParam
User-provided sequence:
10 20 30 40 50 60
MATGAIRQYA QERMDKTYAM FLNDISGIRT GRVSASLLDG ISVSYYGNKV KLNTVSSISV
70 80 90 100 110 120
NGRTLLVSLW DASILGEVKS AIEASNMGFG MTCESSTVRL VVPELTNDVR KNLVKMLNKL
130 140 150 160 170 180
AEESKVSIRN IRRDAIERLK SLQDNKEISE DDMHGVSAEI QKITDSFIKK IADAYTSKES
EILG
References and
documentation are available.
Number of amino acids: 184
Molecular weight: 20315.24
Theoretical pI: 7.77
Total number of negatively charged residues (Asp + Glu): 24
Total number of positively charged residues (Arg + Lys): 25
Atomic composition:
Carbon C 880
Hydrogen H 1460
Nitrogen N 248
Oxygen O 284
Sulfur S 8
Formula: C
880H
1460N
248O
284S
8
Total number of atoms: 2880
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 12950
Abs 0.1% (=1 g/l) 0.637, assuming all pairs of Cys residues form cystines
Ext. coefficient 12950
Abs 0.1% (=1 g/l) 0.637, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 45.76
This classifies the protein as unstable.
Aliphatic index: 96.96
Grand average of hydropathicity (GRAVY): -0.212