ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATGAIRQYA QERMDKTYAM FLNDISGIRT GRVSASLLDG ISVSYYGNKV KLNTVSSISV 

        70         80         90        100        110        120 
NGRTLLVSLW DASILGEVKS AIEASNMGFG MTCESSTVRL VVPELTNDVR KNLVKMLNKL 

       130        140        150        160        170        180 
AEESKVSIRN IRRDAIERLK SLQDNKEISE DDMHGVSAEI QKITDSFIKK IADAYTSKES 


EILG 

References and documentation are available.

Number of amino acids: 184

Molecular weight: 20315.24

Theoretical pI: 7.77

Amino acid composition: 
Ala (A)  13	  7.1%
Arg (R)  11	  6.0%
Asn (N)  10	  5.4%
Asp (D)  11	  6.0%
Cys (C)   1	  0.5%
Gln (Q)   4	  2.2%
Glu (E)  13	  7.1%
Gly (G)  11	  6.0%
His (H)   1	  0.5%
Ile (I)  16	  8.7%
Leu (L)  16	  8.7%
Lys (K)  14	  7.6%
Met (M)   7	  3.8%
Phe (F)   3	  1.6%
Pro (P)   1	  0.5%
Ser (S)  22	 12.0%
Thr (T)  10	  5.4%
Trp (W)   1	  0.5%
Tyr (Y)   5	  2.7%
Val (V)  14	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 24
Total number of positively charged residues (Arg + Lys): 25

Atomic composition:

Carbon      C	       880
Hydrogen    H	      1460
Nitrogen    N	       248
Oxygen      O	       284
Sulfur      S	         8

Formula: C880H1460N248O284S8
Total number of atoms: 2880

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    12950
Abs 0.1% (=1 g/l)   0.637, assuming all pairs of Cys residues form cystines


Ext. coefficient    12950
Abs 0.1% (=1 g/l)   0.637, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 45.76
This classifies the protein as unstable.



Aliphatic index: 96.96

Grand average of hydropathicity (GRAVY): -0.212