ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATGQLFSRN TQALFYNYKQ LPIQRMLDFD FLCGRETPSV AGIINPGSEG FQKLFFGQEE 

        70         80         90        100        110        120 
IAIPVHAAIE AACAAHPTAD VFINFASFRS AAASSMAALK QPTIKVVAII AEGVPESDTK 

       130        140        150        160        170        180 
QLIAYARANN KVIIGPATVG GVQAGAFKIG DTAGTIDNII QCKLYRPGSV GFVSKSGGMS 

       190        200        210        220        230        240 
NEMYNTIARV TDGIYEGIAI GGDVFPGSTL SDHILRFNNI PQIKMVVVLG ELGGRDEYSL 

       250        260        270        280        290        300 
VEAMKQGKVT KPVVAWVSGT CARLFKSEVQ FGHAGAKSGG EMESAQAKNQ ALQDAGATVP 

       310        320        330        340        350        360 
TSFEALEVAI KETFDKLVEE GKVSPIKEVT PPQIPEDLSS AIKSGKVRAP THIISTISDD 

       370        380        390        400        410        420 
RGEEPCYAGV PMSSIIEQGY GVGDVISLLW FKRSLPRYCT KFIEICIMLC ADHGPCVSGA 

       430        440        450        460        470        480 
HNTIVTARAG KDLVSSLVSG LLTIGPRFGG AIDDAARYFK DACDRNLTPY EFVEGMKKKG 

       490        500        510        520        530        540 
IRVPGIGHRI KSRDNRDKRV ELLQKFARSN FPAVKYMEYA VQVETYTLSK ANNLVLNVDG 

       550        560        570        580        590        600 
AIGSLFLDLL AGSGMFTKQE IDEIVQIGYL NGLFVLARSI GLIGHTFDQK RLKQPLYRHP 


WEDVLYTK 

References and documentation are available.

Number of amino acids: 608

Molecular weight: 65813.69

Theoretical pI: 7.92

Amino acid composition: 
Ala (A)  58	  9.5%
Arg (R)  27	  4.4%
Asn (N)  20	  3.3%
Asp (D)  29	  4.8%
Cys (C)  10	  1.6%
Gln (Q)  24	  3.9%
Glu (E)  34	  5.6%
Gly (G)  58	  9.5%
His (H)  10	  1.6%
Ile (I)  49	  8.1%
Leu (L)  44	  7.2%
Lys (K)  38	  6.2%
Met (M)  13	  2.1%
Phe (F)  29	  4.8%
Pro (P)  28	  4.6%
Ser (S)  40	  6.6%
Thr (T)  30	  4.9%
Trp (W)   3	  0.5%
Tyr (Y)  18	  3.0%
Val (V)  46	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 63
Total number of positively charged residues (Arg + Lys): 65

Atomic composition:

Carbon      C	      2945
Hydrogen    H	      4674
Nitrogen    N	       794
Oxygen      O	       867
Sulfur      S	        23

Formula: C2945H4674N794O867S23
Total number of atoms: 9303

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    43945
Abs 0.1% (=1 g/l)   0.668, assuming all pairs of Cys residues form cystines


Ext. coefficient    43320
Abs 0.1% (=1 g/l)   0.658, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.03
This classifies the protein as stable.



Aliphatic index: 91.13

Grand average of hydropathicity (GRAVY): -0.012