ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATGQLFSRT TQALFYNYKQ LPVQRMLDFD FLCGRETPSV AGIINPGSEG FQKLFFGQEE 

        70         80         90        100        110        120 
IAIPVHAAIE AACAAHPTAD VFINFASFRS AAASSMAALK QPTIKVVAII AEGVPESDTK 

       130        140        150        160        170        180 
QLIAYARANN KVVIGPATVG GIQAGAFKIG DTAGTIDNII QCKLYRPGSV GFVSKSGGMS 

       190        200        210        220        230        240 
NEMYNTVARV TDGIYEGIAI GGDVFPGSTL SDHILRFNNI PQIKMMVVLG ELGGRDEYSL 

       250        260        270        280        290        300 
VEALKEGKVN KPVVAWVSGT CARLFKSEVQ FGHAGAKSGG EMESAQAKNQ ALIDAGAIVP 

       310        320        330        340        350        360 
TSFEALESAI KETFEKLVEE GKVSPIKEVI PPQIPEDLNS AIKSGKVRAP THIISTISDD 

       370        380        390        400        410        420 
RGEEPCYAGV PMSSIIEQGY GVGDVISLLW FKRSLPRYCT KFIEICIMLC ADHGPCVSGA 

       430        440        450        460        470        480 
HNTIVTARAG KDLVSSLVSG LLTIGPRFGG AIDDAARYFK DACDRNLTPY EFVEGMKKKG 

       490        500        510        520        530        540 
IRVPGIGHRI KSRDNRDKRV ELLQKFARSN FPSVKYMEYA VTVETYTLSK ANNLVLNVDG 

       550        560        570        580        590        600 
AIGSLFLDLL AGSGMFTKQE IDEIVQIGYL NGLFVLARSI GLIGHTFDQK RLKQPLYRHP 


WEDVLYTK 

References and documentation are available.

Number of amino acids: 608

Molecular weight: 65827.75

Theoretical pI: 7.54

Amino acid composition: 
Ala (A)  57	  9.4%
Arg (R)  27	  4.4%
Asn (N)  21	  3.5%
Asp (D)  28	  4.6%
Cys (C)  10	  1.6%
Gln (Q)  21	  3.5%
Glu (E)  36	  5.9%
Gly (G)  58	  9.5%
His (H)  10	  1.6%
Ile (I)  50	  8.2%
Leu (L)  45	  7.4%
Lys (K)  38	  6.2%
Met (M)  13	  2.1%
Phe (F)  29	  4.8%
Pro (P)  28	  4.6%
Ser (S)  41	  6.7%
Thr (T)  29	  4.8%
Trp (W)   3	  0.5%
Tyr (Y)  18	  3.0%
Val (V)  46	  7.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 64
Total number of positively charged residues (Arg + Lys): 65

Atomic composition:

Carbon      C	      2948
Hydrogen    H	      4680
Nitrogen    N	       792
Oxygen      O	       867
Sulfur      S	        23

Formula: C2948H4680N792O867S23
Total number of atoms: 9310

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    43945
Abs 0.1% (=1 g/l)   0.668, assuming all pairs of Cys residues form cystines


Ext. coefficient    43320
Abs 0.1% (=1 g/l)   0.658, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.12
This classifies the protein as stable.



Aliphatic index: 92.25

Grand average of hydropathicity (GRAVY): 0.005