ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATIIDGKAI AEKIRADLAA QVKELQSRGI TPGLATVLVG SDPASEVYVR MKGDACNKLG 

        70         80         90        100        110        120 
MHSVKITRPA ETTEEELLAL INELNNDPAI HGILVQLPLP PQINADRVLE AISPAKDVDG 

       130        140        150        160        170        180 
FHPYNVGRLV TGKPTFQPCT PYGVMVMLQE AGVDLAGKEV VVVGRSNIVG KPVALMCLQR 

       190        200        210        220        230        240 
NATVTICHSK TRDLPGRVRA ADVVIAAVGV PEMIKGDWIK EGAVVIDVGV NRVGEKKLVG 

       250        260        270        280 
DVEFAAAAER ASAITPVPGG VGPMTITMLL HNTLEAAKMA GSGNR 

References and documentation are available.

Number of amino acids: 285

Molecular weight: 29998.97

Theoretical pI: 6.53

Amino acid composition: 
Ala (A)  33	 11.6%
Arg (R)  14	  4.9%
Asn (N)  11	  3.9%
Asp (D)  14	  4.9%
Cys (C)   4	  1.4%
Gln (Q)   7	  2.5%
Glu (E)  17	  6.0%
Gly (G)  27	  9.5%
His (H)   5	  1.8%
Ile (I)  19	  6.7%
Leu (L)  23	  8.1%
Lys (K)  16	  5.6%
Met (M)  10	  3.5%
Phe (F)   3	  1.1%
Pro (P)  18	  6.3%
Ser (S)   9	  3.2%
Thr (T)  16	  5.6%
Trp (W)   1	  0.4%
Tyr (Y)   3	  1.1%
Val (V)  35	 12.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 31
Total number of positively charged residues (Arg + Lys): 30

Atomic composition:

Carbon      C	      1318
Hydrogen    H	      2188
Nitrogen    N	       372
Oxygen      O	       394
Sulfur      S	        14

Formula: C1318H2188N372O394S14
Total number of atoms: 4286

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    10220
Abs 0.1% (=1 g/l)   0.341, assuming all pairs of Cys residues form cystines


Ext. coefficient     9970
Abs 0.1% (=1 g/l)   0.332, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 33.53
This classifies the protein as stable.



Aliphatic index: 104.67

Grand average of hydropathicity (GRAVY): 0.144