ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATLDAEANE EQFGNDQPKS MSGPIIGIIY PPPEVRNIVD KTASFVARNG PEFEARIRQN 

        70         80         90        100        110        120 
ELGNPKFNFL NGGDPYHAYY RHKVNEFREG NDAGITALAS MKQLAVTSAA QQRQQELLKQ 

       130        140        150        160        170        180 
VVEQQFVPKE PPPEFEFIAD PPSISALDLD IVKLTAQFVA RNGRQFLTNL MSREQRNFQF 

       190        200        210        220        230        240 
DFLRPQHSLF QYFTKLLEQY TKVLIPPKDL LGKLRSESAP GRSSMNQVLE QVKYRANWQR 

       250        260        270        280        290        300 
HQEAQRRREE EKIERERVAY AQIDWHDFVV VETVDYQPFE SGNFPPPTNP DEVGARVLME 

       310        320        330        340        350        360 
ERLMDEEGDT EMQIESDDEG DSQANNLLDS GLKLSQMENR VGIQMKNVSS YGQPTGPKRD 

       370        380        390        400        410        420 
NTQVQDMDEA SSDEDTPTTK LQPSVAPMLP PTHDKVVVKK YDPKATQPKQ APMPTDEYLI 

       430        440        450        460        470        480 
SPITGEKIPA SKVSEHMRIG LLDPRWVEQR DKHTVEKINQ DNVFAAGTAI EASLKQLAER 

       490        500        510        520        530        540 
RTDIFGVGDE ETVIGKKLGE EETKKDDRVT WDGHTSSVEA ATRAARANIT LEEQIHQIHK 

       550        560        570        580        590        600 
VKGLLPDEEK EKIGPKPVGN KATLSAPPQP STKSQHSHSS QSQHHQGGGG GHHGHHNPHH 

       610        620        630        640        650        660 
HHPPHQQAPP HQSHHHHPPQ QPQPVMQLMQ LRPTMMQPPF GAGGGGYMNM QPGGIPQQIA 

       670        680        690        700        710        720 
PAPPVDIMEE EPPSKKIRSE DNLIPEADFI ATHKSPVTIQ VLVPNSDKSE WKLNGQMIAV 

       730        740        750        760        770        780 
TMALSEPIAN LKTKLQDETG MPPAKQKIFY EGMFFKDSNT MAFYNLVNGT TVHLQVKERG 


GRKK 

References and documentation are available.

Number of amino acids: 784

Molecular weight: 88076.00

Theoretical pI: 5.93

Amino acid composition: 
Ala (A)  52	  6.6%
Arg (R)  37	  4.7%
Asn (N)  35	  4.5%
Asp (D)  43	  5.5%
Cys (C)   0	  0.0%
Gln (Q)  62	  7.9%
Glu (E)  65	  8.3%
Gly (G)  50	  6.4%
His (H)  31	  4.0%
Ile (I)  37	  4.7%
Leu (L)  49	  6.2%
Lys (K)  52	  6.6%
Met (M)  26	  3.3%
Phe (F)  27	  3.4%
Pro (P)  68	  8.7%
Ser (S)  44	  5.6%
Thr (T)  40	  5.1%
Trp (W)   5	  0.6%
Tyr (Y)  15	  1.9%
Val (V)  46	  5.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 108
Total number of positively charged residues (Arg + Lys): 89

Atomic composition:

Carbon      C	      3864
Hydrogen    H	      6071
Nitrogen    N	      1111
Oxygen      O	      1197
Sulfur      S	        26

Formula: C3864H6071N1111O1197S26
Total number of atoms: 12269

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    49850
Abs 0.1% (=1 g/l)   0.566

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 50.63
This classifies the protein as unstable.



Aliphatic index: 66.43

Grand average of hydropathicity (GRAVY): -0.813