ProtParam
User-provided sequence:
10 20 30 40 50 60
MATLFLYSNT FSFFFITLVS LALLILRQPS RAASCTARPV IFNFGDSNSD TGGLVAGLGY
70 80 90 100 110 120
PIGFPNGRLF FRRSTGRLSD GRLLIDFLCQ SLNTSLLRPY LDSLGRTRFQ NGANFAIAGS
130 140 150 160 170 180
PTLPKNVPFS LNIQVKQFSH FKSRSLELAS SSNSLKGMFI SNNGFKNALY MIDIGQNDIA
190 200 210 220 230 240
RSFARGNSYS QTVKLIPQII TEIKSSIKRL YDEGGRRFWI HNTGPLGCLP QKLSMVKSKD
250 260 270 280 290 300
LDQHGCLVSY NSAATLFNQG LDHMCEELRT ELRDATIIYI DIYAIKYSLI ANSNQYGFKS
310 320 330 340 350 360
PLMACCGYGG TPYNYNVKIT CGHKGSNVCE EGSRFISWDG IHYTETANAI VAMKVLSMHY
370
SKPPTPFHFF CRR
References and
documentation are available.
Number of amino acids: 373
Molecular weight: 41575.75
Theoretical pI: 9.47
Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 39
Atomic composition:
Carbon C 1868
Hydrogen H 2900
Nitrogen N 510
Oxygen O 531
Sulfur S 18
Formula: C
1868H
2900N
510O
531S
18
Total number of atoms: 5827
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 35465
Abs 0.1% (=1 g/l) 0.853, assuming all pairs of Cys residues form cystines
Ext. coefficient 34840
Abs 0.1% (=1 g/l) 0.838, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 45.06
This classifies the protein as unstable.
Aliphatic index: 84.24
Grand average of hydropathicity (GRAVY): -0.081