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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATNIGMMDS AYFVGRNEIL TWINDRLHLN LSRVEEAASG AVQCQMLDMT FPGVVPMHKV

70 80 90 100 110 120
NFDAKNEYDM IQNYKVLQDV FNKLKITKPL EINRLVKGRP LDNLEFLQWL KRFCDSINGG

130 140 150 160 170 180
IMNENYNPVE RRSRNGKERS VKGSNKIPKS LQTNNNHPPP NSSSVGLSKA SGPKSAKAAE

190 200 210 220 230 240
VQALSKELVD LKISTDLLEK ERDFYFSKLR DVEILCQTPE LDDLPIVVAV KKILYATDAN

250 260 270
ESALEDAQEY LNQSLGVEDD EAEGNGEQLE EEKTQA


References and documentation are available.

Number of amino acids: 276 Molecular weight: 31080.18 Theoretical pI: 5.08
Amino acid composition: 
Ala (A) 18 6.5% Arg (R) 12 4.3% Asn (N) 23 8.3% Asp (D) 18 6.5% Cys (C) 3 1.1% Gln (Q) 12 4.3% Glu (E) 25 9.1% Gly (G) 14 5.1% His (H) 3 1.1% Ile (I) 13 4.7% Leu (L) 29 10.5% Lys (K) 22 8.0% Met (M) 8 2.9% Phe (F) 8 2.9% Pro (P) 12 4.3% Ser (S) 19 6.9% Thr (T) 9 3.3% Trp (W) 2 0.7% Tyr (Y) 7 2.5% Val (V) 19 6.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 43 Total number of positively charged residues (Arg + Lys): 34 Atomic composition: Carbon C 1359 Hydrogen H 2179 Nitrogen N 377 Oxygen O 433 Sulfur S 11 Formula: C1359H2179N377O433S11 Total number of atoms: 4359 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 21555 Abs 0.1% (=1 g/l) 0.694, assuming all pairs of Cys residues form cystines Ext. coefficient 21430 Abs 0.1% (=1 g/l) 0.690, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.75 This classifies the protein as unstable. Aliphatic index: 85.83 Grand average of hydropathicity (GRAVY): -0.557