ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATPMVSSAG GLLAMLNEPH PVLKLHALSN LNNLVDQFWP EISTSVPIIE SLYEDEEFDL 

        70         80         90        100        110        120 
HQRQLAALLV SKVFYYLGEL NDSLSYALGA GPLFDVSEDS DYVHTLLAKA IDEYASLRSK 

       130        140        150        160        170        180 
AVESNEMVDI DPRLEAIVER MLGKCISDGK YQQAMGIAIE CRRLDKLEEA IIKSDNVQGT 

       190        200        210        220        230        240 
LSYCINVSHS FVNRREYRHE VLSLLVKVYQ KLPSPDYLSI CQCLMFLDEP QGVASILEKL 

       250        260        270        280        290        300 
LRSENKDDAL LALQIAFDLV ENEHQAFLLS VRDRLPAPKT RAVEATQAVE TTIAPNENPS 

       310        320        330        340        350        360 
GDVQMADETP AQTIVHETDP VDATYAERLT KIKGILSGET SIQLTLQFLY SHNKSDLLIL 

       370        380        390        400        410        420 
KTIKQSVEMR NSVCHSATIY ANAIMHAGTT VDTFLRENLD WLSRATNWAK FSATAGLGVI 

       430        440        450        460        470        480 
HRGHLQQGRS LMAPYLPQGG AGGGGSPYSE GGALYALGLI HANHGEGIKQ FLRDSLRSTN 

       490        500        510        520        530        540 
VEVIQHGACL GLGLSALGTA DEEIYDDVKS VLYTDSAVAG EAAGISMGLL LVGTATEKAS 

       550        560        570        580        590        600 
EMLAYAHETQ HEKIIRGLAL GIALTVYGRE EGADTLIEQM TRDQDPIIRY GGMYALALAY 

       610        620        630        640        650        660 
SGTANNKAIR QLLHFAVSDV SDDVRRTAVL ALGFVLYSDP EQTPRIVSLL SESYNPHVRY 

       670        680        690        700        710        720 
GAALAVGISC AGTGLSEAIS LLEPLTSDVV DFVRQGALIA MAMVMVQISE ASDSRVGVFR 

       730        740        750        760        770        780 
RQLEKIILDK HEDTMSKMGA ILASGILDAG GRNVTIRLLS KTKHDKVTAV IGLAVFSQFW 

       790        800        810        820        830        840 
YWYPLIYFIS LAFSPTAFIG LNYDLKVPKF EFMSHAKPSL FEYPKPTTVP TANTAVKLPT 

       850        860        870        880        890        900 
AVLSTSVKAK ARAKKEAEQK AIAEKTSGPE KPVNESGSGK GKASTEKEGD SMQVDSPAAV 

       910        920        930        940        950        960 
EKKAPEPEPA FEILVNPARV VPAQEKYIKL LDDSRYVPVK LAPSGFVLLK DLREHEPEVL 

       970        980        990       1000 
SLTDAPTSTA SPATGTAAAA QGTPASAMAV DDEPQPPQAF EYAS 

References and documentation are available.

Number of amino acids: 1004

Molecular weight: 108977.27

Theoretical pI: 5.23

Amino acid composition: 
Ala (A) 111	 11.1%
Arg (R)  40	  4.0%
Asn (N)  28	  2.8%
Asp (D)  54	  5.4%
Cys (C)   8	  0.8%
Gln (Q)  37	  3.7%
Glu (E)  71	  7.1%
Gly (G)  65	  6.5%
His (H)  24	  2.4%
Ile (I)  54	  5.4%
Leu (L) 114	 11.4%
Lys (K)  51	  5.1%
Met (M)  23	  2.3%
Phe (F)  27	  2.7%
Pro (P)  49	  4.9%
Ser (S)  82	  8.2%
Thr (T)  55	  5.5%
Trp (W)   5	  0.5%
Tyr (Y)  35	  3.5%
Val (V)  71	  7.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 125
Total number of positively charged residues (Arg + Lys): 91

Atomic composition:

Carbon      C	      4847
Hydrogen    H	      7723
Nitrogen    N	      1293
Oxygen      O	      1492
Sulfur      S	        31

Formula: C4847H7723N1293O1492S31
Total number of atoms: 15386

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    80150
Abs 0.1% (=1 g/l)   0.735, assuming all pairs of Cys residues form cystines


Ext. coefficient    79650
Abs 0.1% (=1 g/l)   0.731, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.91
This classifies the protein as stable.



Aliphatic index: 96.82

Grand average of hydropathicity (GRAVY): -0.065