ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATRGEAAAA AAADRDMELF RSGSAPPTVE GAMASAAAAA GDVFLDDELR ADPVYQSYYY 

        70         80         90        100        110        120 
SNAHLNPRLP PPLLSKEDWR SAQHRLRSSA LGGIGDGRRQ PAAAAQGDGL VGLPGIDLDR 

       130        140        150        160        170        180 
QGSFSSIFQY ALHRETSRAM GGLQSDSNIQ SLAEVQNNDS SAHTYASLLG SSLSRSASPD 

       190        200        210        220        230        240 
PELVRRVPSP CLPPIGVKVS ADDKKNNGGS SSFRRSSSAI GESDNLIAAL SGMNLSSSGA 

       250        260        270        280        290        300 
ASGQQTVTQS ELYQDVDNVR KFLFDRQGDQ SNGNQQHSYM KHPEQGHFKA PDGYSANSPN 

       310        320        330        340        350        360 
SSMIRNQINA ASFTSFDNLS AGSGFASPRI GSRSPGGTLS SRQNLVGGSN FLNYNGIGSP 

       370        380        390        400        410        420 
NAATSLQTAI DPSYIQYLQA AEIAAQLAAS CDDPLMASGH LGSSYMDLLG PQKAYASPLL 

       430        440        450        460        470        480 
QSQKNCGYYG NLGFGLGYSG SPLMSPVLPS SPAAPGSPLR HGERSMRMQS GIRNFGGSFG 

       490        500        510        520        530        540 
SWNPDLGGKM NINMMPSLLE EFKSNKSKSY ELSEIAGHVV EFSADQYGSR FIQQKLETAS 

       550        560        570        580        590        600 
TEEKDMVFSE IMPQALTLMT DVFGNYVVQK FFEHGSPTQI KELADQLIGR VLALSLQMYG 

       610        620        630        640        650        660 
CRVIQKAIEV VGLDQQTKMV AELDGHVMRC VRDQNGNHVI QKCIECIPQH AIQFIVSTFY 

       670        680        690        700        710        720 
GQVVMLSTHP YGCRVIQRVL EHCDDPTTQQ IMMDEILQSV CLLAQDQYGN YVVQHVLEHG 

       730        740        750        760        770        780 
KPHERSAIIE KLIGQIVQMS QQKFASNVIE KCLAFGNPVE RQILISEMLG STNESEHLEV 

       790        800        810        820        830        840 
MMKDQFANYV VQKVLETCDD QQREAILTRI KAHLNTLKKY TYGKHIVARV EKLVAAGEKR 

       850 
LGLQPACTSA A 

References and documentation are available.

Number of amino acids: 851

Molecular weight: 92198.74

Theoretical pI: 6.08

Amino acid composition: 
Ala (A)  78	  9.2%
Arg (R)  41	  4.8%
Asn (N)  38	  4.5%
Asp (D)  42	  4.9%
Cys (C)  13	  1.5%
Gln (Q)  61	  7.2%
Glu (E)  42	  4.9%
Gly (G)  72	  8.5%
His (H)  22	  2.6%
Ile (I)  41	  4.8%
Leu (L)  75	  8.8%
Lys (K)  32	  3.8%
Met (M)  28	  3.3%
Phe (F)  27	  3.2%
Pro (P)  41	  4.8%
Ser (S)  95	 11.2%
Thr (T)  26	  3.1%
Trp (W)   2	  0.2%
Tyr (Y)  28	  3.3%
Val (V)  47	  5.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 84
Total number of positively charged residues (Arg + Lys): 73

Atomic composition:

Carbon      C	      4004
Hydrogen    H	      6333
Nitrogen    N	      1151
Oxygen      O	      1268
Sulfur      S	        41

Formula: C4004H6333N1151O1268S41
Total number of atoms: 12797

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    53470
Abs 0.1% (=1 g/l)   0.580, assuming all pairs of Cys residues form cystines


Ext. coefficient    52720
Abs 0.1% (=1 g/l)   0.572, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 53.88
This classifies the protein as unstable.



Aliphatic index: 78.34

Grand average of hydropathicity (GRAVY): -0.327