ProtParam
User-provided sequence:
10 20 30 40 50 60
MATTASQSNC WLLQRRQLDS ITTVLAEMIA TAMLMFLGCM GSVENSVFTN SDFQSALNFG
70 80 90 100 110 120
FVVLICIQCF GCVCGAHLNP AVTLATYVYN MISLPMALAY FVAQMVGAFI GYGLLKAVLP
130 140 150 160 170 180
ESAIYSAENP NGVCLTSLNS TLTPWQGLAV EFLITCVLIS VCCGVWDPRN ATKQDSLPVR
190 200 210 220 230 240
FGLAIACLSL TAGQLTGASM NPVRSFAPAI WNGFWDDHWI YWVGPMAAAL ITSVIYKHAF
250
RRELEESEVD
References and
documentation are available.
Number of amino acids: 250
Molecular weight: 27183.68
Theoretical pI: 4.90
Total number of negatively charged residues (Asp + Glu): 16
Total number of positively charged residues (Arg + Lys): 10
Atomic composition:
Carbon C 1228
Hydrogen H 1896
Nitrogen N 308
Oxygen O 346
Sulfur S 21
Formula: C
1228H
1896N
308O
346S
21
Total number of atoms: 3799
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 49555
Abs 0.1% (=1 g/l) 1.823, assuming all pairs of Cys residues form cystines
Ext. coefficient 48930
Abs 0.1% (=1 g/l) 1.800, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 34.30
This classifies the protein as stable.
Aliphatic index: 101.08
Grand average of hydropathicity (GRAVY): 0.578