ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATTMMTSSA SPPESGELDV ASAVASAAAA LISPMVMPTS MTNGKDMTKT SQILNEYFNM 

        70         80         90        100        110        120 
MVGKRVQLMG DTTSPFSLDT PNPKLMFTPL DLPTTAELMQ RCLAVNPFEA KFREANQKIS 

       130        140        150        160        170        180 
SGSMQPNTSG ANQSLEALEA NGGSQFSGSN AGTMSDLLLK IPQASLQHSP GIFSNMLLNA 

       190        200        210        220        230        240 
GDSEGTTREN LKTADISKLL SVAGDFSAQA PRTADVLNAV LDMHSDRLHT INYLNNKPDF 

       250        260        270        280        290        300 
SALLRSPSSS APNSASVLTN AMAIPSTSGA PFPGTTLLVP PKTVSSYHSP LGASSQPPST 

       310        320        330        340        350        360 
QKSPADGSWD HINGEKQIKK EIPYFNDDAM MLMERSNMSS SGSDQDQSAD MSNAGSTAST 

       370        380        390        400        410        420 
STGNPVGRPQ NGTPGRGRGR GRSTTADMQP DERRNTILER NKAAAVRYRK RKKEEHDDMM 

       430        440        450        460        470        480 
GRVQAMEAEK NQLLAIQTQN QVLRRELERV TALLTERESR CVCLKGVPMS DEQHADHHHR 

       490        500 
NTNGMYSGSD MLNGLGQING MQLKLPKLQ 

References and documentation are available.

Number of amino acids: 509

Molecular weight: 54727.50

Theoretical pI: 6.57

Amino acid composition: 
Ala (A)  46	  9.0%
Arg (R)  26	  5.1%
Asn (N)  33	  6.5%
Asp (D)  27	  5.3%
Cys (C)   3	  0.6%
Gln (Q)  26	  5.1%
Glu (E)  24	  4.7%
Gly (G)  35	  6.9%
His (H)  10	  2.0%
Ile (I)  14	  2.8%
Leu (L)  45	  8.8%
Lys (K)  23	  4.5%
Met (M)  30	  5.9%
Phe (F)  11	  2.2%
Pro (P)  33	  6.5%
Ser (S)  60	 11.8%
Thr (T)  37	  7.3%
Trp (W)   1	  0.2%
Tyr (Y)   6	  1.2%
Val (V)  19	  3.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 51
Total number of positively charged residues (Arg + Lys): 49

Atomic composition:

Carbon      C	      2317
Hydrogen    H	      3762
Nitrogen    N	       690
Oxygen      O	       774
Sulfur      S	        33

Formula: C2317H3762N690O774S33
Total number of atoms: 7576

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    14565
Abs 0.1% (=1 g/l)   0.266, assuming all pairs of Cys residues form cystines


Ext. coefficient    14440
Abs 0.1% (=1 g/l)   0.264, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.18
This classifies the protein as unstable.



Aliphatic index: 65.07

Grand average of hydropathicity (GRAVY): -0.552