ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MATTTTEATK TSSTNGEDQK QSQNLRHQEV GHKSLLQSDD LYQYILETSV YPREPESMKE 

        70         80         90        100        110        120 
LREVTAKHPW NIMTTSADEG QFLNMLIKLV NAKNTMEIGV YTGYSLLATA LALPEDGKIL 

       130        140        150        160        170        180 
AMDVNRENYE LGLPIIEKAG VAHKIDFREG PALPVLDEIV ADEKNHGTYD FIFVDADKDN 

       190        200        210        220        230        240 
YINYHKRLID LVKIGGVIGY DNTLWNGSVV APPDAPMRKY VRYYRDFVLE LNKALAADPR 

       250 
IEICMLPVGD GITICRRIS 

References and documentation are available.

Number of amino acids: 259

Molecular weight: 29155.20

Theoretical pI: 5.13

Amino acid composition: 
Ala (A)  19	  7.3%
Arg (R)  12	  4.6%
Asn (N)  14	  5.4%
Asp (D)  19	  7.3%
Cys (C)   2	  0.8%
Gln (Q)   7	  2.7%
Glu (E)  19	  7.3%
Gly (G)  16	  6.2%
His (H)   6	  2.3%
Ile (I)  19	  7.3%
Leu (L)  25	  9.7%
Lys (K)  16	  6.2%
Met (M)   8	  3.1%
Phe (F)   5	  1.9%
Pro (P)  12	  4.6%
Ser (S)  11	  4.2%
Thr (T)  17	  6.6%
Trp (W)   2	  0.8%
Tyr (Y)  13	  5.0%
Val (V)  17	  6.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 38
Total number of positively charged residues (Arg + Lys): 28

Atomic composition:

Carbon      C	      1295
Hydrogen    H	      2050
Nitrogen    N	       346
Oxygen      O	       398
Sulfur      S	        10

Formula: C1295H2050N346O398S10
Total number of atoms: 4099

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    30495
Abs 0.1% (=1 g/l)   1.046, assuming all pairs of Cys residues form cystines


Ext. coefficient    30370
Abs 0.1% (=1 g/l)   1.042, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.70
This classifies the protein as stable.



Aliphatic index: 92.63

Grand average of hydropathicity (GRAVY): -0.335