ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MAVEELQCII KRCQILEEHD FKEEDFGLFQ LAGQRCIEDG YINQLLEIIQ DEKNKTIIKT 

        70         80         90        100        110        120 
MGWNLVGPVV RCLLRGREED KREECFLIFD LLVKLCNPKE LLLGLLELIE EPSGKQISQI 

       130        140        150        160        170        180 
ILLLLQPLQT VIQKLPNNKA YSAGLALSTL WSQLSLLPVP HSEEQIQADD YGLCQCCRAL 

       190        200        210        220        230        240 
IEFTKPFVAE VASDKEDPAN TKLKDELLKF CFKSLKCPLL TAQFLEQSEE VGNDPFRCFA 

       250        260        270        280        290        300 
SEIIGFLSQI GYPVPQIILN HGRKKRTWDY LEFEEEEDRQ LADSVAALTY LVFVQGIGTD 

       310        320        330        340        350        360 
QLPMVLSPSY LLQLNMEHIE VLLQRTEQSV YSKGLELLET SLLRLEDNSL CYQYLEIKSF 

       370        380        390        400        410        420 
LAVPQGLVKV MTLCPIETLR KTGLAMLQLY IDKLDSQGKY TLFRCLLNTS NHSGVEAFVI 

       430        440        450        460        470        480 
QNIKNQIDLS YKKTHNRWFA GAQLTSLLDL VLSLPEGAET DLLQNSDRIM ASLNLLRYLV 

       490        500        510        520        530        540 
IKDNEDDNQT GLWTELGKIE NNFLQPLHVG LNMSKAHYEA EIKNSQQNSQ AASMCKSVCS 

       550        560        570        580        590 
VTVGGEEIPT MPPEMQLKVL HSALFTFDLI ESVLARVEEL IEIKSKSTSE ENAGMK 

References and documentation are available.

Number of amino acids: 596

Molecular weight: 67579.11

Theoretical pI: 4.89

Amino acid composition: 
Ala (A)  29	  4.9%
Arg (R)  19	  3.2%
Asn (N)  26	  4.4%
Asp (D)  27	  4.5%
Cys (C)  17	  2.9%
Gln (Q)  39	  6.5%
Glu (E)  57	  9.6%
Gly (G)  29	  4.9%
His (H)   9	  1.5%
Ile (I)  38	  6.4%
Leu (L)  96	 16.1%
Lys (K)  38	  6.4%
Met (M)  12	  2.0%
Phe (F)  22	  3.7%
Pro (P)  22	  3.7%
Ser (S)  39	  6.5%
Thr (T)  26	  4.4%
Trp (W)   5	  0.8%
Tyr (Y)  15	  2.5%
Val (V)  31	  5.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 84
Total number of positively charged residues (Arg + Lys): 57

Atomic composition:

Carbon      C	      3022
Hydrogen    H	      4843
Nitrogen    N	       779
Oxygen      O	       910
Sulfur      S	        29

Formula: C3022H4843N779O910S29
Total number of atoms: 9583

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    50850
Abs 0.1% (=1 g/l)   0.752, assuming all pairs of Cys residues form cystines


Ext. coefficient    49850
Abs 0.1% (=1 g/l)   0.738, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 52.16
This classifies the protein as unstable.



Aliphatic index: 107.63

Grand average of hydropathicity (GRAVY): -0.099